Child Health Research Center

儿童健康研究中心

• 批准号: 8497391
• 负责人: ALAN L SCHWARTZ
• 金额: $ 43.2万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-01 至 2017-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8497391
• 关键词: 16 year old; Animal Model; Area; Award; Basic Science; Cellular biology; Child health care; Childhood; Core Facility; Development; Developmental Biology; Disease; Doctor of Medicine; Doctor of Philosophy; Environment; Funding; Generations; Genomics; Goals; Human; Immunology; Knowledge; Leadership; Mentors; NCI Scholars Program; Pathogenesis; Pediatrics; Physicians; Play; Research; Resources; Role; Scientist; Structure; Technology; Training; Universities; Washington; career development; human disease; medical schools; pediatric department; programs

DESCRIPTION (provided by applicant): This is a new application (RFA-HD-13-011) for support of the Child Health Research Center at Washington University School of Medicine. Pediatric physician-scientists play a vital role in advancing knowledge related to child health. There is a national need to stimulate child health research by enhancing the training of young pediatric physician-scientists. This program supports the mentored career development of young pediatric physician-scientists by optimally utilizing the resources of the Washington University School of Medicine as we have done for the past 16 years. The long term goal of our Center is to develop Scholars in human developmental biology. We shall achieve this goal by applying the recent advances in basic sciences (developmental biology, cell biology, immunology, genomics, etc.) to an understanding of the pathogenesis of a broad spectrum of diseases within the Pediatric arena. In order to accomplish this, we shall combine the established areas of investigative strength of Washington University School of Medicine and the Department of Pediatrics. Our Scholar's Program, now sixteen years old, will ultimately close the gap between basic scientists and pediatric clinicians. We have in place a programmatic structure in which bright, motivated, young pediatric scientists flourish in a protected environment supported by exceptional mentors and an institutional culture and organization which optimizes their emergence as leaders in an evolving area of Pediatrics. Alan L. Schwartz, Ph.D., M.D. will serve as P.I. /P.D. and Robert Heuckeroth, M.D., Ph.D. will serve as Training Director. The Center (via this award and matched funds from Washington University School of Medicine) and its Scholars will continue to utilize our institutionally-funded core facilities for generation of animal models of human disease states via new and evolving state-of-the-art technologies. The long term goals of the Center will be realized as its Scholars contribute to the development of and leadership in human developmental biology during the next two or more decades.

描述（由申请人提供）：这是一个新申请（RFA-HD-13-011），以支持华盛顿大学医学院儿童健康研究中心。儿科医师科学家在促进与儿童健康相关的知识方面发挥了至关重要的作用。国家需要通过加强年轻儿科医师科学家的培训来刺激儿童健康研究。该计划通过最佳利用华盛顿大学医学院的资源来支持年轻小儿医师科学家的指导职业发展，就像我们过去16年那样。我们中心的长期目标是发展人类发育生物学学者。我们将通过应用基本科学（发育生物学，细胞生物学，免疫学，基因组学等）的最新进展来实现这一目标，以理解儿科领域中广泛疾​​病的发病机理。为了实现这一目标，我们将结合华盛顿大学医学院和儿科系的调查实力的既定领域。我们的学者计划现年16岁，最终将缩小基础科学家与儿科临床医生之间的差距。我们拥有一个程序化结构，在该结构中，在受到特殊导师和机构文化和组织支持的保护环境中，明亮，有动力的年轻儿科科学家在受保护的环境中蓬勃发展，以优化他们作为不断发展的儿科领域的领导者的出现。 M.D. Alan L. Schwartz博士将担任P.I. /P.D。以及医学博士Robert Heuckeroth博士将担任培训主任。该中心（通过该奖项并与华盛顿大学医学院的资金相匹配）及其学者将继续利用我们的机构资助的核心设施通过新的和不断发展的先进技术来生成人类疾病状态的动物模型。该中心的长期目标将实现，因为其学者在接下来的两十年或更多几十年中为人类发展生物学的发展和领导力做出了贡献。