A Community Partnership to Treat Stroke

治疗中风的社区合作伙伴关系

• 批准号: 8268363
• 负责人: Lesli Elizabeth Skolarus
• 金额: $ 18.74万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8268363
• 关键词: Activase; Adult; African American; American; Area; Awareness; Behavior Therapy; Behavioral; Caring; Church; Clinical Research; Commit; Communities; Development; Development Plans; Disease; Educational Intervention; Enrollment; Ensure; Environment; European; Family; Feasibility Studies; Friends; Future; Goals; Health behavior; Hospitals; Hour; Incidence; Intervention; Investments; Ischemic Stroke; K-Series Research Career Programs; Life; Measures; Mentors; Methodology; Michigan; Morbidity - disease rate; Neurologic; Outcome; Outcome Assessment; Outcome Measure; Paper; Participant; Patients; Plasminogen; Population; Randomized; Recruitment Activity; Research; Research Personnel; Research Project Grants; Resources; Sample Size; Science; Scientist; Simulate; Social Network; Stroke; Symptoms; Testing; Time; Tissues; Training; United States; Universities; Work; Youth; acute stroke; base; behavior change; career; career development; community based participatory research; community organizations; cost; design; disability; effective therapy; experience; faith-based intervention; health disparity; improved; innovation; loved ones; meetings; mortality; multidisciplinary; novel; peer; post stroke; programs; response; satisfaction; stroke education; stroke therapy; success; theories; young adult

DESCRIPTION (provided by applicant): African Americans suffer a disproportionate number of strokes resulting in greater post-stroke disability and mortality compared to European Americans. Despite the fact that tissue plasminogen activase (tPA), decreases post-stroke morbidity, mortality and is cost saving, it is underutilized especially among African Americans who are up to one-fifth as likely to receive tPA as European Americans. The primary reason for the underutilization of acute stroke treatments is delayed patient presentation to the hospital which would be remedied by increasing prompt 911 calls for stroke. If all patients presented to the hospital immediately over 25% of stroke patients would receive tPA compared with the 1-3% that are currently treated. The long-term goal of this career development award is to promote the candidate's development into a clinical and research leader in behavioral interventions focusing on health disparities of neurologic disease. The aims of this project are 1)To develop and validate theory-based stroke education intervention materials and outcome measures that use simulated stroke patient video vignettes; 2)To assess the feasibility and acceptability of a faith-based, scientific theory-driven, peer-led behavioral intervention to increase stroke awareness and behavioral intent to call 911 among African American youth and adults in Flint, Michigan. This project is based on a partnership with Bridges into the Future, an African American faith-based community group in Flint, Michigan who will help to design and pre test novel intervention materials and outcome assessments. Then a single group repeated measures design feasibility study will be conducted to obtain preliminary evidence for the impact of our adapted intervention and to test the novel stroke outcome measure. The candidate is committed to a career as a rigorously trained clinician scientist and requires additional training in order to accomplish her long-term goal of reducing health disparities in neurologic disease via behavioral interventions. A detailed career development plan will promote the candidate's development of expertise in the science of behavioral interventions, advanced statistical analysis and an interdisciplinary understanding of health disparities. The career development plan consists of a multidisciplinary team of experts in each of these areas who will oversee a range of formal coursework, working meetings and practical experiences in these areas to ensure the candidate's future success. Excellent resources of a top university and a mentoring team with demonstrated success in developing junior investigators in these topic areas makes the University of Michigan an ideal environment for this project.

描述（由申请人提供）：与欧洲人相比，非洲裔美国人的中风数量不成比例，导致中风后残疾和死亡率更大。尽管组织纤溶酶原活化酶（TPA）降低了中风后发病率，死亡率和节省成本，但在非洲裔美国人中，尤其是未充分利用的非洲裔美国人，这些非洲裔美国人与欧洲美国人的TPA可能五分之五。急性中风治疗不足的主要原因是延迟患者向医院的介绍，这将通过增加迅速的911中风的呼吁来修复。如果立即出现在医院的所有患者中，超过25％的中风患者将接受TPA，而目前接受治疗的1-3％。该职业发展奖的长期目标是将候选人的发展促进临床和研究领导者的行为干预措施，重点是神经系统疾病的健康差异。该项目的目的是1）开发和验证基于理论的中风教育材料和使用模拟的中风患者视频小插图的结果指标； 2）评估基于信仰的，以科学理论驱动的，同伴领导的行为干预的可行性和可接受性，以提高中风意识和行为意图，以在密歇根州弗林特的非裔美国人青年和成人中致电911。该项目基于与桥梁到未来的合作伙伴关系，这是一个基于非裔美国人信仰的社区团体，位于密歇根州弗林特，他们将帮助设计和预测试新颖的干预材料和结果评估。然后，将进行一组重复措施设计可行性研究，以获得我们改编干预的影响并测试新型中风结果度量的初步证据。候选人致力于作为受过严格训练的临床医生的职业生涯，需要额外的培训，以实现她通过行为干预措施减少神经系统疾病健康差异的长期目标。详细的职业发展计划将促进候选人在行为干预科学，高级统计分析和对健康差异的跨学科理解方面的专业知识的发展。职业发展计划由每个领域的多学科专家团队组成，他们将在这些领域中监督一系列正式的课程，工作会议和实践经验，以确保候选人未来的成功。顶尖大学的优质资源和在这些主题领域发展初级调查人员方面取得成功的指导团队使密歇根大学成为该项目的理想环境。