RANDOMIZED INTERVENTION FOR CHILDREN WITH VESICOURETERAL REFLUX (RIVUR)

对膀胱输尿管反流 (RIVUR) 儿童的随机干预

• 批准号: 8167322
• 负责人: H. Gil Rushton
• 金额: $ 0.05万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-20 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167322
• 关键词: Antibiotics; Blood; Child; Childhood; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Development; Double-Blind Method; Enrollment; Fever; Funding; Grant; Institution; Intervention; Monitor; Participant; Pharmaceutical Preparations; Placebo Control; Placebos; Process; Randomized; Recurrence; Research; Research Personnel; Resources; Services; Source; Trimethoprim-Sulfamethoxazole; United States National Institutes of Health; Urinary tract infection; Urine; Urology; Vesico-Ureteral Reflux; prophylactic; renal scarring; research study; sample collection

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The RIVUR study is a randomized, double-blind, placebo-controlled, multi-center study that will enroll children with febrile/symptomatic urinary tract infection (F/S UTI) and vesicoureteral reflux (VUR). Participants are randomized to receive placebo or study drug (i.e. Sulfamethoxazole-Trimethoprim, the standard UTI prophylactic antibiotic), and are monitored for a 2 year period to evaluate the development of renal scarring and recurrent UTIs. Blood and urine specimen collection, processing, and packaging services were requested from the CNMC Pediatric GCRC for this clinical research study being conducted by the CNMC Division of Urology.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 Rivur研究是一项随机，双盲，安慰剂对照的多中心研究，它将招募患有发热/有症状的尿路感染（F/S UTI）和囊泡级别反流（VUR）的儿童。 参与者被随机接受安慰剂或研究药物（即标准UTI预防性抗生素），并接受了2年的监测，以评估肾脏疤痕和经常性UTI的发展。 CNMC儿科GCRC要求进行血液和尿液标本收集，加工和包装服务，以进行由CNMC泌尿外科部门进行的临床研究。