University of Washington Center for AIDS Research

华盛顿大学艾滋病研究中心

• 批准号: 8069683
• 负责人: KING K. HOLMES
• 金额: $ 19万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-17 至 2011-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8069683
• 关键词: University; Washington; Center; AIDS; Research

The UW/FHCRC CFAR includes the UW Academic Medical Center (UWAMC)-Affiliated Institutions Fred Hutchinson Cancer Research Center, Harborview Medical Center, UW Medical Center, Children's Hospital and Regional Medical Center, and Seattle Biomedical Research Institute, plus the University of Hawaii. The Office of AIDS Research lists 156 HIV/AIDS awards from NIH to the UW and its local affiliates in FY06 for $165,185,715 (132 awards for $146,999,393 were "allowable"), up from $9.1 M in 1988, $25.9M in 1997, and $79.4M in 2001. Our CFAR is located in the Dept of Global Health of the Schools of Medicine and Public Health, and has 321 faculty and research scientist members (including 97 of 98 Pis who received NIH AIDSrelated grants in FY06) and 69 trainee members. This proposal includes 10 funded Cores: A) Administration, B) Developmental. C) Biometrics: D) Clinical Research: E) International: F) Clinical Retrovirology; G) Clinical Epidemiology and Health Services Research: H) Computational Biology, a new core; I) Immunology: and J) Sociobehavioral and Prevention Research (which supports our Community Action Board); and 3 Scientific Programs: (1) Mathematical Modeling for HIV/STD Research: (2) Health Systems and Strategies Research, and (3) a new program on AlPS-Associated Infections and Malignancies. The CFAR provides core services, research training and technical assistance; promotes and facilitates collaborations between research, clinical, and service programs; has helped to develop over 200,000 sq. ft. of facilities for HIV/AIDS research; organizes community relationships; provides strategic planning for these activities; and leverages additional foundation, private, corporate, and institutional funding for HIV/AIDS research programs totaling approximately $50,000,000 in 2006. Strategic planning for HIV/AIDS facilities development, much of it initiated and guided by CFAR leadership, has resulted in over 200,000 sq. ft. of new or renovated space for CFAR members since 1997. Thus, our CFAR's added value is reflected in part not only by the 18-fold increase in total NIH HIV/AIDS research funding from 1988 through 2006 (compared with a 6-fold increase in total NIH AIDS funding during this period), with commensurate increases in facilities at the UWAMC and Affiliates, but also by the leveraging of additional non-NIH funding; by state-of-the-art Core services; by commitment of matching funds from the Department, Schools, and Provost totaling over $650,000 annually for the 2008-13 period; and by waiver of indirect costs on New Investigator Awards by affiliated institutions. Our CFAR is increasingly effective, continuing to innovate, uniquely global, and committed to national, cross-CFAR initiatives such as C-NICS, the AIDS-Related Malignancy Working Group, the Socio-Behavioral Sciences Research Network, and specifically involving the CFAR Global AIDS Research Consortium in a new USAID-funded initiative for global Operations Research, Project SEARCH.

UW/FHCRC CFAR 包括 UW 学术医疗中心 (UWAMC) 附属机构 Fred Hutchinson 癌症研究中心、Harborview 医疗中心、UW 医疗中心、儿童医院和地区医疗中心、西雅图生物医学研究所以及夏威夷大学。这 艾滋病研究办公室列出了 2006 财年 NIH 向华盛顿大学及其当地附属机构提供的 156 项艾滋病毒/艾滋病资助，金额为 165,185,715 美元（其中 132 项资助金额为 146,999,393 美元是“允许的”），高于 1988 年的 910 万美元、1997 年的 2590 万美元和 2006 年的 7940 万美元。 2001.我们的CFAR位于医学与公共卫生学院全球健康系，拥有 321 名教职人员和研究科学家成员（包括 2006 财年获得 NIH 艾滋病相关资助的 98 名 Pis 中的 97 名）和 69 名实习生成员。该提案包括 10 个受资助的核心：A) 管理，B) 发展。 C) 生物识别： D) 临床研究： E) 国际： F) 临床逆转录病毒学； G) 临床流行病学和卫生服务研究： H) 计算生物学，新核心； I) 免疫学：和 J) 社会行为和预防研究（支持我们的社区 行动委员会）； 3 个科学计划：(1) HIV/STD 研究的数学模型：(2) 卫生系统和策略研究，以及 (3) AlPS 相关感染和恶性肿瘤的新计划。 CFAR提供核心服务、研究培训和技术援助；促进和促进研究、临床和服务项目之间的合作；帮助开发了超过 200,000 平方英尺的艾滋病毒/艾滋病研究设施；组织社区关系；为这些提供战略规划 活动; 2006 年，为艾滋病毒/艾滋病研究计划筹集了额外的基金会、私人、企业和机构资金，总额约为 50,000,000 美元。艾滋病毒/艾滋病设施发展的战略规划，其中大部分是由 CFAR 领导层发起和指导的，已导致超过 200,000 平方英尺的空间。自 1997 年以来，我们为 CFAR 会员提供了 4 平方英尺的新建或翻新空间。因此，我们的 CFAR 的附加值不仅部分体现在 18 倍的增长上1988 年至 2006 年 NIH 艾滋病毒/艾滋病研究经费总额（相比之下，在此期间 NIH 艾滋病经费总额增加了 6 倍），UWAMC 及其附属机构的设施也相应增加，但也通过利用额外的非 NIH资金;由最先进的核心 服务；系、学校和教务长承诺在 2008-13 年度期间每年提供总额超过 650,000 美元的配套资金；并免除附属机构新研究者奖的间接费用。我们的 CFAR 日益有效、不断创新、具有全球性，并致力于国家跨 CFAR 倡议，例如 C-NICS、艾滋病相关恶性肿瘤工作组、社会行为科学研究网络，特别是 CFAR Global 的参与艾滋病研究联盟参与了由美国国际开发署资助的一项新的全球运营研究计划——Project SEARCH。