Case/UHC Center for AIDS Research

案例/UHC 艾滋病研究中心

• 批准号: 8093104
• 负责人: JONATHAN KARN
• 金额: $ 12.11万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8093104
• 关键词: Acquired Immunodeficiency Syndrome; Africa; Ants; Area; Arts; Award; Bioethics; Biological Assay; Biometry; Caring; Clinic; Clinical; Clinical Research; Clinical Trials Unit; Collaborations; Communication; Comprehensive Cancer Center; Core Facility; Databases; Development; Disease; Education and Outreach; Epidemiology; Ethics; Faculty; Fostering; Foundations; Funding; Future; Gene Expression; HIV; Health Promotion; Hospitals; Immune; Immunology; Immunotherapy; Individual; Infection; Institution; International; International AIDS; Joints; Kenya; Laboratories; Laws; Leadership; Link; Malignant Neoplasms; Medical Research; Medical center; Medicine; Molecular Virology; Mycoses; Pathogenesis; Patient Care; Patients; Performance; Positioning Attribute; Prevention; Prevention Research; Provider; Report (account); Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Sampling; Schools; Services; Site; Specimen; The science of Mycology; Time; Training; Training Support; Training and Education; Translational Research; Tuberculosis; Uganda; United Kingdom; United States; United States National Institutes of Health; Universities; University Hospitals; Vaccines; Work; base; chemotherapy; design; epidemiology study; experience; forging; global health; immune function; instrumentation; interest; medical schools; meetings; member; novel; outreach; programs; repository; restoration; skin disorder; success; user-friendly; volunteer; working group

The CWRU/UHC CFAR has established a unique research program with key strengths in intemational research, ITuberculosis, clinical/translational research and in training. A 16 year close collaboration between CWRU and Makerere IUniversity in Uganda has a fostered an effective HIV research infrastructure in Kampala. An effective Fogarty AIDS pntemational Training and Research Program (AIRTP) with at least 30 degree graduates now working in Africa has also promoted an enhanced level of HIV research, HIV care and prevention in Uganda. In Cleveland and Uganda, through the Tuberculosis Research Unit, key studies of epidemiology, pathogenesis and therapy for this leading co-morbid infection late also undertaken by the CFAR. CWRU investigators also are leading novel NCI-sponsored trials of chemotherapy fow I/kiDS-related malignancy in Uganda and Kenya. The CWRU/UHC CFAR has also developed one of the most productive Iclinicalcores in the CFAR network that has supported more than 120 separate clinical and translational research projects Idudng this period of award because of its unique and patient-care/research data base, a linked specimen repository an_ seamless access to patient volunteers and clinical samples rrhe CFAR leadership (Steering Committee) that comprises both the Core Directors and leaders of 7 scientific working groups assures that scientific needs and directions of the Center are coordinated with service needs and resources. Six CFAR service cores are each designed to provide CWRU investigators with user-friendly access to state of the art services and facilities both in Cleveland and in Kampala. These cores: Uganda Laboratory, Clinical, Biosafety, Immune Function, Epidemiology/Biostatistics and the new Molecular Virology and Gene Expression are led by expedenced investigators and provide quality services that include on-site training and range from access to instrumentation for experienced users to full service performance of assays for infrequent users to meet investigators' individual needs. Ar Administrative Core coordinates and supports CFAR activities through communications, reporting, accounting ant outreach. A Developmental Core provides support and training for new researchers, which is supplemented by generou., institutional funding. Strong institutional support is reflected in a nearly $15 million commitment by CWRU and UHC to the CFAR. The CFAF provides added value to the national and international AIDS research effort through its provision of scientific leadership infrastructure dedicated to AIDS research that provides facilities and resources, including some that are not available a other CFARs, and well-oganized sponsorship of training, education and outreach.

CWRU/UHC CFAR已建立了一项独特的研究计划，具有直接研究，ITUBORCULOSIS，临床/转化研究和培训方面的关键优势。 CWRU和Makerere之间的16年密切合作 乌干达的Iuniversity在坎帕拉有一个有效的HIV研究基础设施。有效的Fogarty AIDS Pntemational培训和研究计划（AIRTP），至少有30位在非洲工作的毕业生也 在乌干达促进了艾滋病毒研究，艾滋病毒护理和预防的增强水平。在克利夫兰和乌干达，通过结核病研究部门，这种主要的合并感染的流行病学，发病机理和治疗的关键研究 CFAR也迟到了。 CWRU研究人员也是领先的新型NCI赞助的化学疗法试验 我/儿童有关的恶性肿瘤在乌干达和肯尼亚。 CWRU/UHC CFAR也开发了最有生产力的 CFAR网络中的IclinicalCores支持了120多个独立的临床和转化研究项目 这段奖项偶然，因为它具有独特的患者护理/研究数据库，这是一个链接的标本存储库 无缝访问患者志愿者和临床样本 RRHE CFAR领导委员会（指导委员会）由7个科学工作组的核心主管和领导者组成，并确保该中心的科学需求和方向与服务需求和资源协调。六 CFAR服务核心均旨在为CWRU调查人员提供在克利夫兰和坎帕拉的用户友好访问最先进的服务和设施。这些核心：乌干达实验室，临床，生物安全，免疫功能，流行病学/生物统计学以及新的分子病毒学和基因表达由高速调查人员领导，并提供了质量服务，包括现场培训和范围从有经验的用户访问仪器的范围内，范围从经验丰富的用户到不及时的分析用户的全面服务，以满足调查员的个人需求。 ar 行政核心坐标并通过通信，报告，会计蚂蚁外展来支持CFAR活动。发展核心为新研究人员提供了支持和培训，该研究人员由机构资金补充。 CWRU和UHC对CFAR的近1500万美元承诺反映了强大的机构支持。 CFAF通过提供科学领导才能为国家和国际艾滋病研究工作增添价值 致力于提供设施和资源的艾滋病研究的基础设施，包括一些其他CFAR，以及培训，教育和外展的良好赞助。