Recipient Epidemiology and Donor Evaluation Study III (REDS-III) Domestic Hub

受赠者流行病学和捐助者评估研究 III (REDS-III) 国内中心

基本信息

批准号：
8655043
负责人：
MAST ALAN
金额：
$ 358.83万
依托单位：
VERSITI WISCONSIN, INC.
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-03-15 至 2017-03-14
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8655043
关键词：
Adult Affect Allogenic Amendment Area Basic Science Biological Sciences Blood Blood Banks Blood Donations Blood Transfusion Cancer Center Cardiac Surgery procedures Clinical Research Clinical Sciences Collection Community Hospitals Confidentiality Contractor Contracts Country Data Data Collection Data Coordinating Center Data Element Data Security Development Education Educational Activities Ensure Epidemic Epidemiology Evaluation Studies Grant HIV Health Insurance Portability and Accountability Act Health Personnel Hospitals Institutional Review Boards Intensive Care Units International Investigation K-Series Research Career Programs Knowledge Laboratories Laboratory Study Leadership Manuals Medical Medicine Mentors National Heart, Lung, and Blood Institute Orthopedic Surgery procedures Outpatients Participant Pathologic Patient Care Patients Performance Policy Developments Population Principal Investigator Procedures Process Protocols documentation Public Health Publications Research Research Activity Research Methodology Research Personnel Risk Safety Series Services Shipping Ships Surveys System Training Training and Education Transfusion Translational Research Trauma Voting Work base data management evidence base evidence based guidelines improved meetings member oncology operation population based programs repository research study symposium tertiary care

项目摘要

The objectives of the REDS-III program are to ensure safe and effective blood banking and transfusion medicine practices through a comprehensive, multi-targeted strategy involving basic, translational, and clinical research to improve the benefits of transfusion while reducing its risks. Improving blood component safety and availability in the U.S. and internationally through the conduct of epidemiologic, survey, and laboratory studies is the cornerstone of the REDS program. Transfusion therapy is the most commonly employed, and, arguably, one of the least understood medical procedures in the U.S. affecting about five million recipients annually. This research program is not only critical to public health in the U.S. but also to countries struggling with the HIV epidemic where blood safety and availability are major concerns. The REDS-III program is comprised of one Data Coordinating Center (DCC), one Central Laboratory, four domestic hubs, and three international collaborative programs involving U.S. investigators and investigators at international blood centers. The REDS-III program will target the following blood banking and transfusion medicine areas: donor targeted strategies; blood banking; transfusion practices in adult patients; and education and training.

REDS-III计划的目标是通过一项涉及基本，转化和临床研究的全面，多目标的策略来确保安全有效的血液库和输血医学实践，以提高输血的好处，同时降低其风险。通过流行病学，调查和实验室研究，改善美国和国际上的血液成分安全性和国际上的可用性是REDS计划的基石。输血疗法是最常见的，并且可以说是美国最了解的医疗程序之一，每年都会影响约500万接受者。该研究计划不仅对美国的公共卫生至关重要，而且对在艾滋病毒流行病上挣扎的国家是主要问题。 REDS-III计划由一个数据协调中心（DCC），一个中央实验室，四个国内枢纽和三个国际合作计划组成，其中涉及国际血液中心的美国调查人员和研究人员。 REDS-III计划将针对以下血液银行和输血医学领域：捐助者针对性的策略；血库；成年患者的输血习惯；以及教育和培训。