Improving Outcome Measurement for Medical Rehabilitaiton Clinical Trials

改善医疗康复临床试验的结果测量

• 批准号: 8470201
• 负责人: ALAN Maurice JETTE
• 金额: $ 73.78万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-23 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8470201
• 关键词: Boston; Clinical Research; Clinical Trials; Collaborations; Complex; Educational workshop; Effectiveness; Ensure; Goals; Hospitals; Intervention; Measurement; Measures; Medical; Medicine; Methods; Online Systems; Outcome; Outcome Measure; Patient Outcomes Assessments; Performance; Pilot Projects; Policy Maker; Process; Rehabilitation Outcome; Rehabilitation therapy; Research; Research Personnel; Resources; Scientist; Time; Training; Training Activity; Universities; Visit; base; design; improved; innovation; instrument; medical schools; programs; systematic review; technique development; theories

The Boston Network for contemporary rehabilitation outcome measurement (the Boston CRO Network), a collaboration among researchers from Boston University, Harvard Medical School/ Spaulding Rehabilitation Hospital, and Tufts University, would greatly enhance the capability of medical rehabilitation researchers to understand outcome measures, develop and refine measures of key rehabilitation outcomes, and improve their use in rehabilitation medicine clinical trials and related research. This theme is particularly relevant given the demand from payers, policy makers, clinicians and consumers for evidence to support the effectiveness of rehabilitation interventions. The timing of its formation is ideal, given the recent advances in patient reported outcomes, innovations in performance-based outcome measures, and instrumented outcome measures have made it possible to overcome many of the limitations of traditional outcome measures. The selection of outcome measures for clinical trials remains a complex process, and most rehabilitation clinicians and researchers lack training to ensure the appropriate measures are used. The Boston CRO Network would provide medical rehabilitation researchers with access to resources, training and technical support to improve the selection and use of CROs in rehabilitation clinical trials to assist with increasing the number and quality of successfully completed RCTs in the field of medical rehabilitation. The Boston CRO Network consists of a Research Core, a Techniques Development Section, a Training & Didactic Core, and an Administrative Core. The Research Core would include a Patient Reported Outcomes Core, a Performance-based Measures Core, and an Instrumented Outcomes Measurement Core along with Pilot Studies and Visiting Scientist Programs. The Training & Dissemination Core will conduct systematic reviews of CROs, establish a web-based CRO Instrument Clearinghouse; conduct training workshops & webcasts, and widely disseminate Boston CRO Network resources, pilot project results and training activities. The goal of the Boston CRO Network is to provide resources, training and technical support with the aim of increasing the number and quality of successfully completed rehabilitation RCTs.

波士顿当代康复结果测量网络（波士顿 CRO 网络）是波士顿大学、哈佛医学院/斯波尔丁康复医院和塔夫茨大学的研究人员之间的合作，将极大地提高医疗康复研究人员了解结果测量、开发治疗结果的能力。细化康复关键结局指标，提高其在康复医学临床试验及相关研究中的应用。 鉴于付款人、政策制定者、临床医生和消费者对支持康复干预措施有效性的证据的需求，这一主题尤为重要。鉴于患者报告结果的最新进展、基于绩效的结果测量的创新以及仪器化结果测量使得克服传统结果测量的许多局限性成为可能，其形成的时机是理想的。临床试验结果指标的选择仍然是一个复杂的过程，大多数康复临床医生和研究人员缺乏培训来确保使用适当的措施。波士顿CRO网络将为医疗康复研究人员提供资源、培训和技术支持，以改善康复临床试验中CRO的选择和使用，协助提高医疗康复领域成功完成的随机对照试验的数量和质量。 波士顿 CRO 网络由研究核心、技术开发部分、培训和教学核心以及行政核心组成。研究核心将包括患者报告结果核心、基于绩效的衡量核心、仪器化结果衡量核心以及试点研究和访问科学家计划。培训和传播核心将对CRO进行系统审查，建立基于网络的CRO工具信息交换所；举办培训研讨会和网络广播，并广泛传播波士顿 CRO 网络资源、试点项目成果和培训活动。波士顿 CRO 网络的目标是提供资源、培训和技术支持，以提高成功完成的康复随机对照试验的数量和质量。