Research Training in Pediatric Oncology

儿科肿瘤学研究培训

• 批准号: 8288591
• 负责人: STUART H ORKIN
• 金额: $ 51.71万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-13 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8288591
• 关键词: Pediatric Oncology; Research Training

DESCRIPTION (provided by applicant): This is a new application for training grant support with a single mission: the goal of this T32 program is to train physicians who will be the future academic leaders in basic and/or clinical pediatric oncology research. Reducing the burden of cancer in the pediatric population requires necessitates research across the entire spectrum from fundamental molecular and cellular biologic studies to translational work that bridges the gulf that separates basic research and clinical medicine to clinical investigation. Reducing the burden of cancer in pediatric populations requires broad and intensive training of academic pediatric physicians. An experienced and highly accomplished group of faculty including faculty of the Department of Pediatric Oncology at the Dana Farber Cancer Institute (DFCI), the Division of Pediatric Hematology/Oncology at Children's Hospital Boston (CHB), and additional components of the Harvard Medical School constitute the training faculty for this program. This faculty encompasses basic, translational, and clinical investigation. Trainees will be selected from the combined DFCI-CHB pediatric hematology/oncology fellowship program. Particular emphasis is placed on close mentorship of trainees in the selection of mentors and in on-going oversight during their research. The program is committed to identifying and supporting the most promising fellows, including minority candidates. Over the past 40 years the DFCI-CHB fellowship program has trained >200 individuals, many of whom are leaders and academic pediatric medicine. The proposed T32 program will ensure the continuance and further development of the fellowship program, and promises to contribute immeasurably to the management of children with cancer. While great strides have been made in diagnosis and treatment of pediatric cancers, much remains to be done. Cure of patients is often achieved with unacceptable side-effects, and for many solid tumors current therapy is inadequate. The best hope for reducing the burden of pediatric cancer is the training of committed researchers by an experienced and accomplished faculty that is involved in diverse aspects of basic and clinical research directly relevant to tackling these challenging problems in children.

描述（由申请人提供）：这是一项新的培训赠款支持的应用程序：该T32计划的目标是培训那些将成为基本和/或临床儿科肿瘤学研究的未来学术领导者的医生。减轻儿科人群中癌症的负担需要在整个范围内进行研究，从基本分子和细胞生物学研究到翻译工作，这些工作将基础研究和临床医学分开到临床研究的海湾桥梁。减轻儿科人群中癌症的负担需要对学术医生进行广泛而深入的培训。一群经验丰富且成就卓著的教职员工，包括Dana Farber癌症研究所（DFCI）的儿科肿瘤学系，波士顿儿童医院（CHB）的儿科血液学/肿瘤学系以及哈佛大学医学院的其他成分构成了该计划的培训学院。该教师涵盖了基本，转化和临床研究。将从组合的DFCI-CHB儿科血液学/肿瘤学奖学金计划中选出学员。特别重点是对学员的仔细指导，并在研究过程中进行了持续的监督。该计划致力于识别和支持最有前途的研究员，包括少数派候选人。在过去的40年中，DFCI-CHB奖学金计划培训了200个人，其中许多是领导者和学术医学。拟议的T32计划将确保奖学金计划的继续和进一步发展，并有望为患有癌症儿童的管理做出无可估计的贡献。 尽管在诊断和治疗小儿癌症方面取得了长足的进步，但仍有许多事情要做。经常通过不可接受的副作用来治愈患者，对于许多实体瘤，当前治疗不足。减轻儿科癌症负担的最佳希望是，经验丰富且有成就的教师培训了忠实的研究人员，该教师参与了与解决儿童中这些具有挑战性问题的基础和临床研究的各个方面。