Research Training in Pediatric Oncology

儿科肿瘤学研究培训

• 批准号: 8288591
• 负责人: STUART H ORKIN
• 金额: $ 51.71万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-13 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8288591
• 关键词: Pediatric Oncology; Research Training

DESCRIPTION (provided by applicant): This is a new application for training grant support with a single mission: the goal of this T32 program is to train physicians who will be the future academic leaders in basic and/or clinical pediatric oncology research. Reducing the burden of cancer in the pediatric population requires necessitates research across the entire spectrum from fundamental molecular and cellular biologic studies to translational work that bridges the gulf that separates basic research and clinical medicine to clinical investigation. Reducing the burden of cancer in pediatric populations requires broad and intensive training of academic pediatric physicians. An experienced and highly accomplished group of faculty including faculty of the Department of Pediatric Oncology at the Dana Farber Cancer Institute (DFCI), the Division of Pediatric Hematology/Oncology at Children's Hospital Boston (CHB), and additional components of the Harvard Medical School constitute the training faculty for this program. This faculty encompasses basic, translational, and clinical investigation. Trainees will be selected from the combined DFCI-CHB pediatric hematology/oncology fellowship program. Particular emphasis is placed on close mentorship of trainees in the selection of mentors and in on-going oversight during their research. The program is committed to identifying and supporting the most promising fellows, including minority candidates. Over the past 40 years the DFCI-CHB fellowship program has trained >200 individuals, many of whom are leaders and academic pediatric medicine. The proposed T32 program will ensure the continuance and further development of the fellowship program, and promises to contribute immeasurably to the management of children with cancer. While great strides have been made in diagnosis and treatment of pediatric cancers, much remains to be done. Cure of patients is often achieved with unacceptable side-effects, and for many solid tumors current therapy is inadequate. The best hope for reducing the burden of pediatric cancer is the training of committed researchers by an experienced and accomplished faculty that is involved in diverse aspects of basic and clinical research directly relevant to tackling these challenging problems in children.

描述（由申请人提供）：这是一项新的培训拨款支持申请，其使命只有一个：该 T32 计划的目标是培训将成为基础和/或临床儿科肿瘤学研究未来学术领导者的医生。减轻儿科人群的癌症负担需要进行全方位的研究，从基础分子和细胞生物学研究到弥合基础研究和临床医学与临床研究之间鸿沟的转化工作。减轻儿科人群的癌症负担需要对学术儿科医师进行广泛而深入的培训。哈佛医学院由经验丰富、成就卓著的教师团队组成，其中包括达纳法伯癌症研究所 (DFCI) 儿科肿瘤科、波士顿儿童医院 (CHB) 儿科血液学/肿瘤科的教师以及哈佛医学院的其他部门该计划的培训师资。该学院涵盖基础、转化和临床研究。学员将从 DFCI-CHB 儿科血液学/肿瘤学联合奖学金项目中选拔。在导师的选择和研究过程中的持续监督方面，特别强调对受训者的密切指导。该计划致力于识别和支持最有前途的研究员，包括少数族裔候选人。在过去的 40 年里，DFCI-CHB 奖学金计划已培训了超过 200 名人员，其中许多人是儿科医学领域的领导者和学术界人士。拟议的 T32 计划将确保该奖学金计划的继续和进一步发展，并承诺为癌症儿童的管理做出不可估量的贡献。 尽管在儿科癌症的诊断和治疗方面取得了巨大进步，但仍有许多工作要做。患者的治愈常常伴随着不可接受的副作用，并且对于许多实体瘤来说，目前的治疗是不够的。减轻儿科癌症负担的最佳希望是由经验丰富且有成就的教师培训忠诚的研究人员，这些教师参与与解决这些具有挑战性的儿童问题直接相关的基础和临床研究的各个方面。