VirtualDose Software for Diagnostic CT Doses to Adults and Children

用于成人和儿童诊断 CT 剂量的 VirtualDose 软件

基本信息

批准号：
8462245
负责人：
Xie George Xu
金额：
$ 12.16万
依托单位：
VIRTUAL PHANTOMS, INC.
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2015-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8462245
关键词：
10 year old 15 year old 5 year old Accounting Adopted Adult Age Algorithms American American College of Radiology Awareness Body Image Body Size Cancer Center Chest Child Childhood Clinical Clinical Protocols Collimator Communities Comparative Study Computer software Computing Methodologies Data Reporting Databases Development Diagnostic Diagnostic Imaging Discipline of Nuclear Medicine Dose Exposure to Family Female Filtration Florida Funding Future Goals Heating Human body Image Incidence Individual Institutes Knowledge Manufacturer Name Marketing Measurable Measurement Medical Medical Imaging Medicine Methods Modality Modeling New York Obesity Organ Organ Model Patients Phase Photons Physics Population Pregnant Women Procedures Protocols documentation Radiation Radiation Protection Radiation therapy Radiation-Induced Cancer Radiology Specialty Recommendation Registries Reporting Research Research Activity Research Personnel Rest Risk Roentgen Rays Role Scanning Shapes Small Business Technology Transfer Research Societies Software Design Software Engineering Surveys System Technology Technology Transfer Three-Dimensional Image Time Tissues Tomography, Computed, Scanners Tube United States National Institutes of Health Universities X-Ray Computed Tomography base design detector graphical user interface imaging modality improved ionization male meetings member model design patient population pregnant programs public health relevance radiologist risk selection sex simulation software systems success tool trend user-friendly virtual

项目摘要

DESCRIPTION (provided by applicant): This project aims to develop a commercial software product, VirtualDoseTM, for calculating and analyzing patient radiation doses from x-ray computed tomography (CT) examinations. Despite its essential role in radiology, CT is responsible for raising the collective medical radiation dose to the American population to a level that is associated with measurable and predictable risk for carcinogenic effect today. Accurate knowledge and record of patient organ doses have now become critical in the successful and sustainable use of this imaging modality. It is recognized that existing software are insufficient in meeting the current and future needs involving modern MDCT scanners. Based on unique "virtual patient" technologies and extensive Monte Carlo modeling capabilities and modern software engineering, this proposed software system is expected to improve upon the accuracy and functionality in CT dose estimates. Specific aims of the project are: (1) To adopt a family of anatomically realistic phantoms including the adult male/female, pregnant female, and male/female children with the capability to adjust the body size and shape. (2) To develop a Monte Carlo based computational method for modeling various CT scanners and clinical protocols. (3) To establish a comprehensive organ dose database by using the Monte Carlo CT scanner models and ICRP algorithms. (4) To develop and refine the software graphical user interfaces by using 3D object- oriented programming.

描述（由申请人提供）：该项目旨在开发一种商业软件产品 VirtualDoseTM，用于计算和分析 X 射线计算机断层扫描 (CT) 检查中的患者辐射剂量。尽管 CT 在放射学中发挥着重要作用，但 CT 仍负责将美国人口的集体医疗辐射剂量提高到与当今可测量和可预测的致癌作用风险相关的水平。准确了解和记录患者器官剂量现已成为成功和可持续使用这种成像方式的关键。人们认识到，现有软件不足以满足现代 MDCT 扫描仪当前和未来的需求。基于独特的“虚拟患者”技术和广泛的蒙特卡罗建模功能以及现代软件工程，该软件系统预计将提高 CT 剂量估计的准确性和功能。该项目的具体目标是：（1）采用一系列解剖学逼真的模型，包括成年男性/女性、怀孕女性、以及能够调整身体大小和形状的男性/女性儿童。 (2) 开发基于蒙特卡罗的计算方法，用于对各种 CT 扫描仪和临床协议进行建模。 (3)利用蒙特卡罗CT扫描仪模型和ICRP算法建立综合的器官剂量数据库。 (4) 使用3D面向对象编程技术开发和完善软件图形用户界面。