PROMIS Pediatrics: Longitudinal Validation and Linking Pediatric and Adult Item B

PROMIS 儿科：纵向验证以及链接儿科和成人项目 B

基本信息

批准号：
8705695
负责人：
Bryce B Reeve
金额：
$ 20万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-30 至 2016-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8705695
关键词：
Abbreviations Acute Adolescent Adult Affect Asthma Award Child Child Language Child health care Childhood Childhood Asthma Chronic Disease Clinical Clinical Research Clinical Sciences Communication Data Collection Disease Disease remission Equation Evaluation Factor Analysis Fatigue Florida Focal Segmental Glomerulosclerosis Future Grant Health Policy Health Status Link Longitudinal Studies Malignant Neoplasms Measures Medical center Methods Modeling Nephrology Nephrotic Syndrome North Carolina Pain Patient Outcomes Assessments Pediatric Hospitals Pediatrics Principal Investigator Quality of life Questionnaires Recovery Relapse Research Research Personnel Sickle Cell Anemia State Children&apos s Health Insurance Program Testing Translational Research Universities Validation Work base chemotherapy design health related quality of life instrument novel response theories trait

项目摘要

DESCRIPTION (provided by applicant): The overall objectives of this project are to validate the PROM IS pediatric item banks in 4 pediatric chronic illnesses, and to link pediatric and adult item banks. We developed 9 pediatric item banks during the first PROMIS grant cycle and have performed cross-sectional testing in children with several chronic illnesses. The proposed work is the natural next step toward integration of PROMIS scales into clinical research. We propose longitudinal studies in children with asthma, cancer, nephrotic syndrome, and sickle cell disease. Each study follows children through a clinical transition known to affect health-related quality of life, and each study will examine the responsiveness of the PROMIS instruments and estimate the minimum important difference (MID) for children. As part of these studies, we have proposed to test a new method for establishing MID and to compare that method with traditional distributional and anchor-based methods. The second overall objective is to link PROMIS pediatric item banks with PROMIS adult item banks. We designed most of the pediatric banks to measure the same underlying trait as their counterpart adult banks (e.g., fatigue), but used the concepts and language of children. We will administer pediatric and adult short forms to adolescents with chronic illnesses with a cross-sectional data collection. For this objective, we will use factor analysis and structural equation modeling to establish the empirical relationships between the pediatric and adult item banks and domains, and, to the extent supported by those relationships, use item response theory to link the pediatric and adult item banks. This study will enable researchers to have comparable scores between children and adults participating in the same study and enable longitudinal studies that follow children into adulthood.

描述（由申请人提供）：该项目的总体目标是验证舞会是4种儿科慢性病的小儿物品库，并将儿科和成人物品库联系起来。在第一个Promis赠款周期中，我们开发了9个小儿物品库，并在患有多种慢性疾病的儿童中进行了横断面测试。拟议的工作是将Promis量表整合到临床研究中的自然下一步。我们提出在患有哮喘，癌症，肾病综合征和镰状细胞病的儿童的纵向研究。每项研究都会跟随儿童进行临床过渡，已知会影响与健康相关的生活质量，每项研究将检查Promis工具的反应性，并估计儿童的最小重要差异（MID）。作为这些研究的一部分，我们建议测试一种新方法，以建立中间和将该方法与传统的分布和基于锚的方法进行比较。第二个总体目标是将Promis小儿物品库与Promis成人商品银行联系起来。我们设计了大多数儿科银行，以测量与成人银行（例如疲劳）相同的基本特征，但使用了儿童的概念和语言。我们将向患有横断面数据收集的慢性疾病的青少年进行儿科和成人短形式。为了实现这一目标，我们将使用因子分析和结构方程建模来建立儿科和成人物品库和领域之间的经验关系，并在这些关系支持的范围内使用项目响应理论将小儿和成人物品库联系起来。这项研究将使研究人员能够在参与同一研究的儿童和成人之间具有可比的分数，并能够跟随儿童成年后的纵向研究。

项目成果

期刊论文数量（29）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

An item response analysis of the pediatric PROMIS anxiety and depressive symptoms scales.

DOI：
10.1007/s11136-010-9619-3
发表时间：
2010-05
期刊：
QUALITY OF LIFE RESEARCH
影响因子：
3.5
作者：
Irwin, Debra E.;Stucky, Brian;Langer, Michelle M.;Thissen, David;DeWitt, Esi Morgan;Lai, Jin-Shei;Varni, James W.;Yeatts, Karin;DeWalt, Darren A.
通讯作者：
DeWalt, Darren A.

PROMIS® Parent Proxy Report Scales for children ages 5-7 years: an item response theory analysis of differential item functioning across age groups.

DOI：
10.1007/s11136-013-0439-0
发表时间：
2014-02
期刊：
QUALITY OF LIFE RESEARCH
影响因子：
3.5
作者：
Varni, James W.;Thissen, David;Stucky, Brian D.;Liu, Yang;Magnus, Brooke;Quinn, Hally;Irwin, Debra E.;DeWitt, Esi Morgan;Lai, Jin-Shei;Amtmann, Dagmar;Gross, Heather E.;DeWalt, Darren A.
通讯作者：
DeWalt, Darren A.

Sampling plan and patient characteristics of the PROMIS pediatrics large-scale survey.

DOI：
10.1007/s11136-010-9618-4
发表时间：
2010-05
期刊：
QUALITY OF LIFE RESEARCH
影响因子：
3.5
作者：
Irwin, Debra E.;Stucky, Brian D.;Thissen, David;DeWitt, Esi Morgan;Lai, Jin Shei;Yeatts, Karin;Varni, James W.;DeWalt, Darren A.
通讯作者：
DeWalt, Darren A.

Determinants of longitudinal health-related quality-of-life change in children with asthma from low-income families: a report from the PROMIS® Pediatric Asthma Study.

低收入家庭哮喘儿童与健康相关的生活质量纵向变化的决定因素：PROMIS® 小儿哮喘研究的报告。

DOI：
10.1111/cea.12827
发表时间：
2017
期刊：
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
影响因子：
0
作者：
Li,Z;Leite,WL;Thompson,LA;Gross,HE;Shenkman,EA;Reeve,BB;DeWalt,DA;Huang,I-C
通讯作者：
Huang,I-C

Longitudinal Effect of Ambient Air Pollution and Pollen Exposure on Asthma Control: The Patient-Reported Outcomes Measurement Information System (PROMIS) Pediatric Asthma Study.