Genes, the Environment, and ME (GEM)

基因、环境和 ME（GEM）

• 批准号: 8478224
• 负责人: Stephanie Malia Fullerton
• 金额: $ 24.59万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8478224
• 关键词: Address; Adopted; Affect; Age; Agriculture; Animal Model; Area; Attitude; Behavior; Bioethics; Biology; Biomedical Research; Clinical; Collaborations; Communication; Communities; Complex; Data; Development; Disease; Educational Curriculum; Educational process of instructing; Ensure; Environment; Environmental Health; Environmental Risk Factor; Epigenetic Process; Ethical Issues; Ethicists; Ethics; Family; Family member; Festival; Fostering; Genes; Genetic; Genome; Goals; Health; Health Policy; Health Sciences; Heart Diseases; Hispanic Americans; Human; Individual; Institution; Instruction; Knowledge; Lead; Learning; Life; Life Style; Link; Malignant Neoplasms; Minority; Modeling; Native Americans; Non-Insulin-Dependent Diabetes Mellitus; Organism; Outcome; Parents; Pathway interactions; Population; Population Heterogeneity; Poverty; Problem Solving; Public Health; Public Health Practice; Research Design; Risk; Rural; School Teachers; Schools; Science; Scientist; Series; Societies; Students; Teacher Professional Development; Thinking; Translating; Translational Research; Underrepresented Minority; United States; Universities; Washington; Work; after-school program; base; career; community based participatory research; design; experience; gene environment interaction; genetic analysis; graduate student; high school; improved; interest; meetings; member; middle school; outreach; programs; public health relevance; research study; science education; skills; teacher; trait; undergraduate student

DESCRIPTION (provided by applicant): The Department of Genome Sciences at the University of Washington (UW) proposes a five year project, Genes, the Environment, and Me (GEM). This project will address the pressing need for deeper understanding of biomedical research among diverse populations and increased representation of underrepresented minorities in biomedical fields through a school and community-focused science education program. The project will be conducted in collaboration with three programs within the UW Office of Minority Affairs and Diversity, the UW Center for Ecogenetics and Environmental Health, and scientists and ethicists at the UW and other biomedical research institutions throughout Washington. GEM will use a Community-Based Participatory Research Approach to involve community members-teachers, students, parents, and community leaders-as equal partners in planning, developing, and implementing project activities. Through these partnerships, we will develop a series of modular lessons focused on a fundamental concept of biology-the interaction of genes and the environment in the determination of traits in all living organisms. The lessons will be used to supplement health and science programs that serve underrepresented K-12 students throughout Washington and other parts of the United States. In addition, Family Science Festivals will involve students, teachers, families, and the community in learning about genetic concepts and health-related conditions in an informal all- age celebration. GEM will work primarily with school districts in the Yakima Valley, a rural agricultural region in central Washington with a high percentage of Hispanic and Native American students, many from high poverty families with limited English proficiency and low educational attainment levels. Complex diseases (i.e. those caused a combination of genetic and environmental factors) such as type 2 diabetes, heart disease, and cancer are important health problems for Hispanic and Native American people, making the teaching of gene- environment interactions an especially compelling topic for this population. GEM will focus primarily on middle and high school students and their teachers to promote deeper understanding of genetic concepts, including how genes and the environment interact to determine traits. Engagement in genetics activities and discussions of ethical issues that affect individuals and society will help students to formulate ideas about their own identity, attitudes, and interests, including career interests. Washington's teaching and learning standards require teachers to incorporate genetic concepts at these grade levels, and therefore they are eager to have well designed lessons to supplement their curriculum. Exposing students, particularly those from traditionally underrepresented communities, to linked career options may encourage some to pursue advanced studies in science and math and ultimately a career in a biomedical field.

描述（由申请人提供）：华盛顿大学（UW）的基因组科学系提出了一个为期五年的项目，基因，环境和我（GEM）。该项目将通过学校和以社区为重点的科学教育计划对生物医学研究中的生物医学研究进行更深入的了解，并增加对生物医学领域中代表性不足的少数群体的代表性的迫切需求。该项目将与UW UW UW办公室内的三个计划，UW生态学与环境健康中心以及UW和其他生物医学研究机构的科学家和伦理学家合作进行。 GEM将使用基于社区的参与研究方法参与社区成员，学生，父母和社区领袖 - 作为计划，开发和实施项目活动的平等合作伙伴。通过这些伙伴关系，我们将开发一系列的模块化课程，重点是生物学的基本概念 - 基因的相互作用与环境在所有生物体中的性状确定中。这些课程将用于补充健康和科学计划，为在华盛顿和美国其他地区提供代表性不足的K-12学生提供服务。此外，家庭科学节将使学生，老师，家庭和社区在非正式的全年级庆祝活动中了解遗传概念和与健康相关的状况。 GEM将主要与华盛顿中部农村农村地区Yakima Valley的学区合作，其中包括西班牙裔和美洲原住民学生的比例很高，其中许多来自高贫困家庭，英语水平有限，教育程度较低。复杂的疾病（即导致遗传因素和环境因素的结合），例如2型糖尿病，心脏病和癌症对西班牙裔和美洲原住民来说是重要的健康问题，这使得基因环境相互作用的教学是该人群特别令人信服的话题。 GEM将主要关注中学生及其老师，以促进对遗传概念的更深入的了解，包括基因和环境如何相互作用以确定特征。参与影响个人和社会的道德问题的遗传学活动和讨论将帮助学生制定有关自己身份，态度和兴趣（包括职业利益）的想法。华盛顿的教学标准要求教师在这些年级水平上纳入遗传概念，因此他们渴望获得精心设计的课程来补充课程。暴露学生，尤其是从传统代表性不足的社区的学生到联系的职业选择，可能会鼓励一些人从事科学和数学领域的高级研究，并最终从事生物医学领域的职业。