A Novel Adherence Technology for Ophthalmic Medications

一种新型眼科药物依从性技术

基本信息

批准号：
8589227
负责人：
Michael Bailey
金额：
$ 20.49万
依托单位：
CARE TEAM SOLUTIONS, LLC
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-09-30 至 2015-03-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8589227
关键词：
Address Adherence Back Blindness Caregivers Caring Chronic Disease Chronically Ill Companions Complex Computer software Data Development Devices Disease Dose Drops Drug Containers Drug Delivery Systems Drug Stability Drug usage Electronics Elements Engineering Ensure Evaluation Event Eye Eyedrops Focus Groups Funding Funding Category Generations Glaucoma Health Health Care Costs Heating Home environment Housing Injectable Intellectual Property Intervention Label Leadership Light Liquid substance Medication Management Mind Mission Modeling Monitor Names Ointments Optic Nerve Oral Outcome Participant Patients Pharmaceutical Preparations Phase Physiologic Intraocular Pressure Proliferating Protocols documentation Public Health Reading Refrigeration Regimen Reporting Research Personnel Self-Administered Self-Help Devices Small Business Innovation Research Grant Solutions Sterility Suspension substance Suspensions System Technology Telephone Testing Therapeutic Time United States National Institutes of Health Vial device Vision Visual impairment Visually Impaired Persons base combat comorbidity compliance behavior effectiveness measure experience improved innovation medication compliance novel ophthalmic drug pill point of care prevent prototype public health relevance satisfaction skills telehealth usability web site

项目摘要

ABSTRACT Technological aids supporting medication management for chronically ill patients are proliferating, offered in electronic telehealth devices. Pill organizers, reminders, monitors, and usage communicators have enabled an array of home health aids to support users and caregivers in pill management and monitoring. Beyond bulk pills, additional medication forms, such as topicals, are gaining popularity in unique drug delivery systems. However, topical medications have limited electronic monitoring means for promoting and tracking adherence even though the consequences of nonadherence are just as alarming as with oral meds. For example, glaucoma is a leading cause of blindness worldwide, yet patient compliance with topical medication regimens is suboptimal at best. Ophthalmic drug adherence is daunting due to several unique barriers: 1) complexity-- the application of eye drops can be highly complicated involving multiple drugs taken several times daily, 2) administration-- visually impaired patients often cannot correctly identify medication and read labels, 3) lability-- many drugs react adversely to extreme conditions, and 4) lack of patient options-- no multi-drug container exists with feature-rich reminding, monitoring, and intervention functions. Moreover, a primary barrier to administration of eye drops is the problematic issue of actually administering drops properly. This project will leverage our world-class medication adherence system and our team's exceptional skill sets and experience in developing an ophthalmic medication dispensing system that will instruct, remind, monitor, communicate, and report in a highly affordable, practical, and user-sensitive model. It includes a drop dispensing device that assures only one drop is properly applied to the eye in sterile, safe, and correct application with infrared monitoring.

抽象的支持长期病人的药物管理的技术辅助工具正在扩散，提供电子远程医疗设备。药丸组织者，提醒，监视器和用法传播者已启用一系列家庭健康援助，以支持药丸管理和监测的用户和护理人员。超越散装药丸，其他药物形式（例如局部用药形式）在独特的药物输送系统中广受欢迎。但是，局部药物具有有限的电子监测方法来促进和跟踪依从性即使不遵守的后果与口服药物一样令人震惊。例如，青光眼是全球失明的主要原因，但患者遵守局部药物方案是最多次优。通过几个独特的障碍，眼科药物的依从性令人生畏：1）复杂性 - 眼滴的应用可能是高度复杂的，涉及每天服用多种药物，2）管理 - 视力障碍患者通常无法正确识别药物并阅读标签，3）劳动力 - 许多药物对极端情况和4）缺乏患者选择不利 - 没有多药存在具有丰富功能的提醒，监视和干预功能的容器。而且，主要眼滴管理的障碍是正确管理下降的问题问题。这项目将利用我们的世界一流的药物依从性系统以及我们团队的卓越技能和在开发眼科药物分配系统的经验，该系统将指示，提醒，监视，通过高度实用，实用和用户敏感的模型进行交流和报告。它包括一个滴在无菌，安全和校正的情况下，仅确保仅保证一滴一滴的设备适当地应用于眼睛使用红外监控应用。