Development of a Mobile System for Self-management of Schizophrenia (SOS)

开发精神分裂症自我管理移动系统（SOS）

• 批准号: 8488042
• 负责人: Dror Ben-Zeev
• 金额: $ 22.94万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-15 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8488042
• 关键词: Address; Adherence; Adult; Antipsychotic Agents; Car Phone; Caring; Chronic; Delusions; Development; Devices; Distress; Effectiveness; Ensure; Environment; Feedback; Focus Groups; Functional disorder; Funding; Future; General Population; Goals; Hallucinations; Health; Hour; Impairment; Individual; Intervention; Laboratories; Learning; Location; Mental Health; Mental disorders; Modeling; Modification; Outcome; Patients; Penetration; Pharmaceutical Preparations; Pharmacotherapy; Population; Preparation; Procedures; Protocols documentation; Psychiatric Social Work; Psychotic Disorders; Randomized; Randomized Controlled Trials; Regimen; Research; Respondent; Schizophrenia; Self Management; Series; Severities; Social Functioning; Staging; Structure; Surveys; Symptoms; System; Technology; Testing; Therapeutic; Time; Training; Treatment outcome; Work; base; coping; cost; design; evidence base; functional disability; improved; interest; medication compliance; mental health center; novel; operation; pilot trial; prototype; psychosocial; public health relevance; severe mental illness; skills; social; standard care; tool; treatment as usual; usability; week trial

DESCRIPTION (provided by applicant): Schizophrenia is associated with staggeringly high individual and societal costs. Antipsychotic medications are considered the primary intervention for long-term treatment of schizophrenia, but long-term treatment outcomes are often poor. A large body of research suggests illness-management strategies can support pharmacotherapies by reducing the severity and distress associated with persistent psychotic symptoms, improve social functioning at various stages of the illness, and enhance medication adherence. Unfortunately, these illness-management interventions are rarely available at mental health centers. Mobile technologies are ubiquitous and may be tremendously instrumental in increasing the accessibility and utilization of effective psychosocial interventions for schizophrenia. Mobile interventions have already been successfully developed and deployed to support the self-management of a number of chronic health conditions as well as several mental health conditions. The goal of the proposed project is to develop and pilot a mobile system for Self- Management of Schizophrenia (SOS) with the ultimate objective of creating a widely-available tool that can be deployed by users as needed, in their own environments. Individuals with schizophrenia will provide input on planned intervention content as well as the structure and style of the proposed system. Expert consultants will review and provide feedback to ensure content is grounded in effective evidence-based approaches and the technical complexity is appropriate for the target audience. Laboratory and field tests will be conducted to identify and resolve technical problems, and to determine acceptability and feasibility of the SOS system in real-world conditions. Following appropriate modifications, a randomized pilot trial of SOS compared to treatment as usual will be conducted with individuals with schizophrenia. All aspects of the intervention protocol will be examined, including functionality, recruitment and retention procedures, and preliminary effectiveness of the mobile intervention on outcomes, in preparation for a subsequent larger randomized controlled trial. The proposed project will introduce a model of treatment which offers illness-management strategies at any time and in any location, allowing for ongoing, as well as "on-demand" therapeutic support. If effective, the SOS system could improve individuals' ability to effectively manage their illness when they are not receiving psychosocial services, or enhance the potency of care when offered as adjunct to standard treatments. The long-term goals of the project are to create a validated application that can be easily downloaded onto a mobile phone and used by anyone, facilitating wide-scale and far-reaching implementation and dissemination of evidence-based tools.

描述（由申请人提供）：精神分裂症与个人和社会成本惊人的相关。抗精神病药被认为是长期治疗精神分裂症的主要干预措施，但长期治疗结果通常很差。大量研究表明，疾病管理策略可以通过减少与持续的精神病症状相关的严重性和困扰，改善疾病的各个阶段的社交功能并增强药物依从性来支持药物治疗。不幸的是，这些疾病管理干预措施在心理健康中心很少获得。移动技术无处不在，可能在增加对精神分裂症有效的心理心理干预措施的可及性和利用方面具有极大的作用。移动干预措施已经成功开发和部署，以支持许多慢性健康状况以及多种心理健康状况的自我管理。拟议项目的目的是开发和试行一个用于精神分裂症（SOS）自我管理的移动系统，其最终目标是创建一个可根据自己的环境中的用户可以根据需要部署的广泛可用工具。精神分裂症患者将提供有关计划的干预内容以及拟议系统的结构和样式的意见。专家顾问将审查并提供反馈，以确保内容以有效的基于证据的方法为基础，并且技术复杂性适合目标受众。将进行实验室和现场测试，以识别和解决技术问题，并确定在现实情况下SOS系统的可接受性和可行性。经过适当的修改后，将与往常进行治疗相比，对SOS进行随机试验试验，将与精神分裂症患者进行。将检查干预方案的所有方面，包括功能，招聘和保留程序，以及移动干预对结果的初步有效性，以准备随后进行更大的随机随机对照试验。拟议的项目将引入一种治疗模型，该模型随时和任何位置提供疾病管理策略，允许持续进行以及“按需”治疗支持。如果有效，SOS系统可以提高个人在不接受心理社会服务时有效管理疾病的能力，或者在作为标准治疗的辅助手术时提高护理能力。该项目的长期目标是创建一个经过验证的应用程序，该应用程序可以轻松地下载到手机上并由任何人使用，从而促进广泛而深远的实施以及对循证工具的传播。