Developmental Research Program

发展研究计划

• 批准号: 8588556
• 负责人: Sissy M Jhiang
• 金额: $ 8.83万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-25 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8588556
• 关键词: Advertising; Applications Grants; Automobile Driving; Basic Science; Cancer Center; Cancer Patient; Caring; Development; Diagnosis; Elements; Ensure; Funding; Goals; Institution; Investigation; Lead; Malignant neoplasm of thyroid; Mission; Monitor; Ohio; Outcome; Patients; Peer Review; Pilot Projects; Population Sciences; Prevention; Process; Quality of life; Research; Research Personnel; Resources; Source; TNFRSF5 gene; Technology; Therapeutic; Translating; Translational Research; Universities; University of Texas M D Anderson Cancer Center; expectation; high risk; improved; innovation; new technology; outcome forecast; programs; success

The Developmental Research Program (DRP) is an essential component to ensure the continuous success of The Ohio State University/MD Anderson Thyroid Cancer SPORE application. By soliciting and supporting high risk and high impact developmental projects, the DRP will infuse new ideas, new resources, and new technologies that are the driving elements of translational research. The fully developed projects will also provide the SPORE Director with a renewable source of projects that can replace existing SPORE projects, which have been completed or have not fulfilled specific translational expectations. The mission of this SPORE application is to improve therapeutic outcome and life quality for patients with thyroid cancer. Accordingly, the DRP will seek to fund a broad range of proposals from basic science investigation, population science, and innovative approaches that can be translated into better prevention, diagnosis, prognosis, and experimental therapeutics. Drs. Jhiang and Sherman will serve as Co-Leaders to implement an effective DRP. The aims of DRP are: (1) develop a rigorous process to advertise the available resources of the SPORE and to solicit proposals from investigators of broad range of expertise; (2) define a rigorous peer-review process to select meritorious proposals and to monitor annual progress of funded proposals; and (3) provide assistance to promote the funded proposals into full projects within the SPORE or into nationally funded independent grant applications. With the requested SPORE DRP fund and institutional commitnients from OSUCCC and MDACC, we anticipate in funding two new proposals in the year 1 and year 3, one new proposal in the years 2, 4, and 5. Accordingly, a total of seven DRP proposals will be funded throughout the five-year funding period of the SPORE. The two DRPs selected for year 1 are both technology driven, which will lead to new research direction and/or provide new avenue for our battle against thyroid cancer RELEVANCE (See instrucllons): The Developmental Research Program is a component of this Thyroid Cancer SPORE that will fund pilot projects to assist researchers exploring new ideas that will be eventually translated into a better care for thyroid cancer patients. The program will solicit proposals, review, provide funding and promote further development of the selected projects.

发展研究计划 (DRP) 是确保持续成功的重要组成部分 俄亥俄州立大学/MD 安德森甲状腺癌 SPORE 应用。通过征求和支持 高风险、高影响的发展项目，DRP将注入新理念、新资源和新成果 技术是转化研究的驱动要素。全面开发的项目也将 为 SPORE 总监提供可替代现有 SPORE 项目的可再生项目来源， 已完成或未达到特定翻译期望的项目。本次活动的使命 SPORE的应用是为了改善甲状腺癌患者的治疗结果和生活质量。 因此，DRP 将寻求资助基础科学调查、 人口科学和创新方法可以转化为更好的预防、诊断、 预后和实验治疗。博士。 Jhiang 和 Sherman 将作为联合领导人来实施 有效的 DRP。 DRP 的目标是： (1) 制定严格的流程来宣传可用资源 SPORE 并征求具有广泛专业知识的调查人员的建议； (2) 严格定义 同行评审过程，以选择有价值的提案并监测受资助提案的年度进展； (3) 提供协助，将资助的提案推广为 SPORE 内的完整项目或纳入 国家资助的独立拨款申请。根据要求的 SPORE DRP 基金和机构 在 OSUCCC 和 MDACC 的承诺下，我们预计在第一年和第二年资助两项新提案 第 3 年，第 2 年、第 4 年和第 5 年提出一项新提案。因此，总共将资助 7 项 DRP 提案 SPORE 的整个五年资助期内。第一年选择的两个 DRP 都是 技术驱动，这将带来新的研究方向和/或为我们的斗争提供新的途径 甲状腺癌 相关性（参见说明）： 发展研究计划是甲状腺癌孢子的一部分，将为试点项目提供资金 帮助研究人员探索新想法的项目，这些新想法最终将转化为更好的护理 甲状腺癌患者。该计划将征求建议、审查、提供资金并进一步促进 选定项目的开发。