Methods Core

方法核心

• 批准号: 8129681
• 负责人: GAIL E. WYATT
• 金额: $ 41.43万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-13 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8129681
• 关键词: Acute; Arts; Behavioral; Biological; Biological Markers; Biological Process; Child; Child Sexual Abuse; Childhood; Chronic stress; Cognitive; Collaborations; Development; Disclosure; Emotional; Ethnic group; Event; Future; Interdisciplinary Study; Intervention; Latina; Latino; Life; Longitudinal Studies; Mediator of activation protein; Mental Depression; Mental Health; Mental Health Services; Mentors; Methods; Minority; Mothers; Outcome; Pilot Projects; Post-Traumatic Stress Disorders; Prevalence; Recording of previous events; Recruitment Activity; Research; Research Personnel; Role; Self Disclosure; Source; Symptoms; Trauma; Violence; Woman; allostatic load; cohort; coping; emotional disclosure; ethnic difference; ethnic minority population; experience; health care service utilization; health disparity; help-seeking behavior; intimate partner violence; longitudinal course; men; psychologic; psychological distress; sexual trauma; statistics; trauma centers

DESCRIPTION (provided by applicant): We propose to establish a five-year, multi-ethnic and multi-disciplinary "Collaborative Center for Trauma and Mental Health" (CCTMHD) to promote interdisciplinary research examining the prevalence and impact of traumatic experiences on PTSD, depression and concomitant cognitive/emotional, behavioral, psychological and biological processes in ethnic minority populations. The overarching aim is to inform new strategies to reduce mental health disparities associated with trauma exposure. Multiple sources of acute and chronic stress combine to have a cumulative effect in the lives of ethnic minorities, giving rise to our use of the conceptual framework of allostatic load to (1) describe the socio-cultural context in which violence occurs; (2) examine cultural differences in the appraisal of traumatic events; (3) identify protective and vulnerability factors within ethnic groups; and (4) characterize the expression of mental health symptoms and help-seeking that contribute to mental health disparities. The Center, led by Dr. Gail Wyatt in collaboration with an experienced team of minority mental health researchers includes an Administrative Core, which will coordinate and integrate all Center activities including mentoring of investigators and a Methods & Statistics Core, which will be responsible for providing methodological support to all Center investigators and projects. Project 1 is a 4-year, longitudinal study, "Intimate Partner Violence and Mental Health Outcomes among Latinas", led by Dr. M. Rodriguez. He will investigate the longitudinal course of PTSD and depression, attachment and related biological sequelae in an existing cohort of 205 Latina mothers, who vary on intimate partner violence histories. Project 2, "Disclosure & Appraisal of Child Sexual Abuse (CSA): Relationships with PTSD, Depression, & Associated Biomarkers" is led by Drs. J. Vargas-Carmona and T. Loeb. This 2-year pilot study focuses on the impact of CSA disclosure and self-blame among 110 Black and Latina women with CSA histories. Project 3, a 2-year pilot study, "Coping among Ethnic Men Sexually Abused as Children", is led by Dr. F. Galvan. He will recruit 150 Latino and Black men to examine ethnic differences in coping strategies and their role as possible moderators or mediators of psychological distress, biological effects of childhood sexual trauma and mental health service utilization. This Center will stimulate state-of-the-art research on trauma and mental health disparities, and inform the development of future interventions to close these gaps.

描述（由申请人提供）：我们建议建立一个为期五年、多种族和多学科的“创伤和心理健康合作中心”（CCTMHD），以促进跨学科研究，审查创伤经历的普遍性和对创伤后应激障碍（PTSD）的影响，少数民族人群的抑郁症以及随之而来的认知/情绪、行为、心理和生物过程。总体目标是提供新策略，以减少与创伤暴露相关的心理健康差异。急性和慢性压力的多种来源结合起来对少数族裔的生活产生累积影响，导致我们使用非稳态负荷的概念框架来（1）描述暴力发生的社会文化背景； (2) 考察创伤事件评估中的文化差异； (3) 识别族群内的保护性和脆弱性因素； (4) 描述导致心理健康差异的心理健康症状和寻求帮助的表现。该中心由盖尔·怀亚特 (Gail Wyatt) 博士领导，与一支经验丰富的少数族裔心理健康研究人员团队合作，包括一个行政核心，负责协调和整合中心的所有活动，包括指导研究人员和方法与统计核心，负责提供为所有中心研究人员和项目提供方法支持。项目 1 是一项为期 4 年的纵向研究，名为“拉丁美洲人的亲密伴侣暴力和心理健康结果”，由 M. Rodriguez 博士领导。他将在现有的 205 名拉丁裔母亲队列中调查 PTSD 和抑郁症、依恋和相关生物后遗症的纵向过程，这些母亲的亲密伴侣暴力史各不相同。项目 2，“儿童性虐待 (CSA) 的披露和评估：与 PTSD、抑郁症和相关生物标志物的关系”由 Drs. 领导。 J. Vargas-Carmona 和 T. Loeb。这项为期 2 年的试点研究重点关注 CSA 披露和自责对 110 名有 CSA 历史的黑人和拉丁裔女性的影响。项目 3 是一项为期 2 年的试点研究，名为“应对儿童时期遭受性虐待的少数民族男性”，由 F. Galvan 博士领导。他将招募 150 名拉丁裔和黑人男性来研究应对策略的种族差异，以及他们作为心理困扰的可能调节者或调解者的作用、儿童性创伤的生物效应以及心理健康服务的利用。该中心将促进对创伤和心理健康差异的最先进研究，并为未来干预措施的发展提供信息，以缩小这些差距。