Research Training Program in Surgical Oncology

肿瘤外科研究培训计划

• 批准号: 8536729
• 负责人: Kirby I. Bland
• 金额: $ 32.06万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8536729
• 关键词: Research Training; Surgical Oncology; Training Programs

DESCRIPTION (provided by applicant): This competitive renewal was originally funded in 2002, and is now completing the fourth year of its second five-year cycle (10th year). This T32 builds upon established clinical and scientific strengths in various oncologic disciplines of the Departments of Surgery and Obstetrics/Gynecology. The partnership of both Departments with UAB Comprehensive Cancer Center provides an integrated infrastructure of collaborative bench science that spans fundamental molecular discovery to move scientific inquiry from bench-to-bedside for applied clinical and translational research. This training environment enhances the intra-collaborative, seamless trans-departmental initiatives available in Tumor Biology and Immunology, Human Genetics, Autoimmunity and Inflammation, Translational Clinical and Outcomes Research. The strategic goals of the research plan have special emphasis on the training of nascent, promising young Surgical-Scientists in their early post-doctoral years and who are in ACGME-approved training programs in Surgery or Gynecologic Oncology. Thus, this T-32 program coordinates the mentorship of promising post- doctoral ACGME resident-candidates who will aspire to academic faculty positions and will strengthen UAB's exceptional mentoring environment. This T-32 grant represents a mechanism for faculty collaboration and synergistic scientific interests among its four SPORE programs at UAB. Programmatically, an effective interdisciplinary research experience is implemented by the obligatory incorporation of the required teaching via mentors and the required course work for individual research plans. Course work in statistics and ethical conduct of research is augmented in this competitive renewal with formal instruction provided by the Center for Clinical and Translational Science (CCTS) and the Office of Post-Doctoral Education in grantsmanship, manuscript writing, and translational research. Over the past five years, 22 ACGME resident-trainees in Surgery and Gynecologic Oncology were supported by this T-32 mechanism. Because post-graduate surgical training approaches 7-10 years, and T-32 Trainees conduct research in the early stages of their career, a significant number of trainees still have >5 years of surgical training remaining prior to academic appointment. Therefore, we are just beginning to see the academic success of our program after 10 years of continuous funding. In the past 10 years, there have been 36 trainees that have completed their T-32 training with 70 % of these residents continuing in academic biomedical research and practice / training. Moreover, in the past five years, this T-32 has been gender-balanced and has included 17% under-represented minorities. This T32 has, over the past ten years, provided continual strong commitment to trainees with oversight and encouragement of reciprocal commitment to careers in investigation and academia. This is reflected by those who have completed training with academic faculty positions in other Schools of Medicine within Departments of Surgery, its oncology disciplines, and Obstetrics/Gynecology. Continued funding is therefore requested annually for 6 post-doctoral resident-trainees.

说明（由申请人提供）：本次竞争性更新最初于 2002 年提供资金，目前即将完成第二个五年周期的第四年（第十年）。该 T32 建立在外科和妇产科各个肿瘤学科的既定临床和科学优势之上。两个部门与 UAB 综合癌症中心的合作提供了协作实验室科学的综合基础设施，涵盖基础分子发现，将科学探究从实验室转移到临床应用和转化研究。这种培训环境增强了肿瘤生物学和免疫学、人类遗传学、自身免疫和炎症、转化临床和结果研究领域的内部协作、无缝跨部门计划。 该研究计划的战略目标特别强调对处于博士后早期阶段、参加 ACGME 批准的外科或妇科肿瘤学培训项目的新生、有前途的年轻外科科学家进行培训。因此，这个 T-32 计划协调对有前途的 ACGME 博士后住院候选人的指导，他们将渴望获得学术教职职位，并将加强 UAB 的卓越指导环境。这项 T-32 拨款代表了 UAB 四个 SPORE 项目之间的教师合作和协同科学兴趣的机制。从计划上来说，有效的跨学科研究经验是通过导师所需的教学和个人研究计划所需的课程工作的强制性结合来实现的。在这次竞争性更新中，临床和转化科学中心 (CCTS) 和博士后教育办公室在资助、手稿写作和转化研究方面提供正式指导，统计和研究道德行为方面的课程工作得到了加强。在过去的五年里，22 名 ACGME 外科和妇科肿瘤科住院实习生得到了 T-32 机制的支持。由于研究生外科培训接近 7-10 年，而 T-32 学员在其职业生涯的早期阶段进行研究，因此相当多的学员在学术任命之前仍有超过 5 年的外科培训。因此，经过 10 年的持续资助，我们才刚刚开始看到我们的项目在学术上取得的成功。在过去的10年里，已有36名学员完成了T-32培训，其中70%的住院医师继续从事学术生物医学研究和实践/培训。此外，在过去的五年里，这个T-32已经实现了性别平衡，并包括了17%的代表性不足的少数族裔。在过去的十年中，T32 为学员提供了持续的坚定承诺，并监督和鼓励他们对调查和学术界的职业生涯做出相互承诺。这反映在那些在其他医学院的外科、肿瘤学科和妇产科内完成学术教职培训的人身上。因此，每年需要为 6 名博士后住院实习生提供持续资助。