Training Grant in Diabetes and Metabolism

糖尿病和新陈代谢培训补助金

基本信息

  • 批准号:
    8500609
  • 负责人:
  • 金额:
    $ 4.9万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1977
  • 资助国家:
    美国
  • 起止时间:
    1977-07-01 至 2017-06-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): In 2011, almost 26 million Americans suffer from diabetes, making it one of our most costly diseases in human and economic terms. To cure and prevent diabetes will require development of a corps of dedicated young diabetes researchers who have received multi-disciplinary training. The Joslin Diabetes Center T32 Training Program in Diabetes and Metabolism aims to attract outstanding young scientists into research on diabetes and metabolism, and train them in a vibrant and collaborative environment in which they are exposed to the many facets of diabetes and its causes. The Joslin Diabetes Center, founded in 1898, is a collaborative and integrated organization that fosters cutting-edge research and outstanding diabetes care, and incorporates a strong research base and a busy clinic in a single facility. Its physical and academic infrastructure is greatly enhanced by Joslin having been supported as a Diabetes and Endocrine Research Center (DRC) since 1986. The rich training environment of this T32 Program derives not only from Joslin itself, but also from the many close ties and collaborations that Joslin has with Harvard Medical School and many of its affiliated hospitals. In its 35 years of existence this T32 Program has trained many outstanding diabetes researchers, including five members of the current T32 Program Faculty. Our former postdoctoral trainees from the last 10 years have been awarded numerous federal grants (including R01, K99/R00, K08, and F32 awards), and include 12 Assistant or Associate Professors, most of whom are appointed at medical schools. Our pre- and post- doctoral trainees from this time have published many papers in the highest-caliber basic and clinical journals. This application aims to continue and build upon this excellence in training. Since the end of 2008 this T32 program has been directed by T. Keith Blackwell, MD, PhD, an Associate Research Director at Joslin. He is supported by an Executive Committee and an Education Coordinator, and the Joslin Fellowship Selection Committee. The Joslin T32 Program Faculty covers a wide range of interests encompassing Types 1 and 2 diabetes, metabolism, and diabetic complications, and includes basic, clinical, and translational scientists. This applicatio requests support for the same number of training positions as in the last grant period: five postdoctoral slots, two dedicated Pediatric postdoctoral slots, three predoctoral slots, and two short-term slots for summer research. As currently, a mix of MD, MD/PhD, and PhD trainees will be selected from Joslin research groups, endocrinology training programs at Harvard-affiliated hospitals, Harvard PhD programs, and other sources. The proposed Program Plan includes new initiatives for trainee recruitment and education that have been put in place by Dr. Blackwell, including opening the predoctoral program to Joslin/DRC-affiliated labs at nearby Harvard affiliates. These initiatives are designed to strengthen further our trainee base and the training that we offer, bring top young scientists into diabetes research, and foster collaborations among our trainees, Joslin research groups, and other Harvard-affiliated diabetes and metabolism researchers.
描述(由申请人提供):2011 年,近 2600 万美国人患有糖尿病,使其成为人类和经济方面代价最高的疾病之一。为了治愈和预防糖尿病,需要培养一支受过多学科培训的年轻专门糖尿病研究人员队伍。乔斯林糖尿病中心 T32 糖尿病和代谢培训项目旨在吸引优秀的年轻科学家参与糖尿病和代谢研究,并在充满活力和协作的环境中对他们进行培训,让他们接触糖尿病及其病因的许多方面。乔斯林糖尿病中心成​​立于 1898 年,是一个协作和综合组织,致力于促进尖端研究和出色的糖尿病护理,并在一个设施中整合了强大的研究基地和繁忙的诊所。乔斯林大大增强了其物质和学术基础设施 自1986年以来一直作为糖尿病和内分泌研究中心(DRC)获得支持。这个T32项目丰富的培训环境不仅源于Joslin本身,还源于Joslin与哈佛医学院以及许多机构的密切联系和合作。其附属医院。 T32 项目成立 35 年来,培养了许多杰出的糖尿病研究人员,其中包括现任 T32 项目教员的五名成员。我们过去 10 年的前博士后培训生获得了大量联邦资助(包括 R01、K99/R00、K08 和 F32 奖项),其中包括 12 名助理或副教授,其中大多数是在医学院任命的。我们的博士前和博士后学员已在最高水平的基础和临床期刊上发表了许多论文。该应用程序旨在继续并巩固这种卓越的培训。自 2008 年底以来,该 T32 项目一直由 Joslin 副研究主任、医学博士、博士 T. Keith Blackwell 指导。他得到执行委员会和教育协调员以及乔斯林奖学金遴选委员会的支持。 Joslin T32 项目教师涵盖广泛的兴趣,包括 1 型和 2 型糖尿病、新陈代谢和糖尿病并发症,并包括基础、临床和转化科学家。该申请要求支持与上一个资助期相同数量的培训职位:五个博士后职位、两个专门的儿科博士后职位、三个博士前职位和两个用于夏季研究的短期职位。目前,医学博士、医学博士/博士和博士生的混合体将从乔斯林研究小组、哈佛附属医院的内分泌学培训项目、哈佛博士项目和其他来源中选拔。拟议的计划计划包括布莱克韦尔博士实施的实习生招募和教育新举措,包括向附近哈佛附属机构的乔斯林/刚果民主共和国附属实验室开放博士前计划。这些举措旨在进一步加强我们的学员基础和我们提供的培训,让顶尖的年轻科学家参与糖尿病研究,并促进我们的学员、乔斯林研究小组和其他哈佛大学附属糖尿病和代谢研究人员之间的合作。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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T Keith Blackwell其他文献

T Keith Blackwell的其他文献

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{{ truncateString('T Keith Blackwell', 18)}}的其他基金

Identifying metabolic mechanisms that regulate appetite and foodintake
识别调节食欲和食物摄入的代谢机制
  • 批准号:
    10309083
  • 财政年份:
    2021
  • 资助金额:
    $ 4.9万
  • 项目类别:
Identifying metabolic mechanisms that regulate appetite and foodintake
识别调节食欲和食物摄入的代谢机制
  • 批准号:
    10475244
  • 财政年份:
    2021
  • 资助金额:
    $ 4.9万
  • 项目类别:
Homeostasis functions of SKN-1A/Nrf1
SKN-1A/Nrf1 的稳态功能
  • 批准号:
    10803010
  • 财政年份:
    2017
  • 资助金额:
    $ 4.9万
  • 项目类别:
Signaling mechanisms that detect stress and maintain homeostasis
检测压力和维持体内平衡的信号机制
  • 批准号:
    10701725
  • 财政年份:
    2017
  • 资助金额:
    $ 4.9万
  • 项目类别:
Signaling mechanisms that detect stress and maintain homeostasis
检测压力和维持体内平衡的信号机制
  • 批准号:
    10219290
  • 财政年份:
    2017
  • 资助金额:
    $ 4.9万
  • 项目类别:
Signaling mechanisms that detect stress and maintain homeostasis
检测压力和维持体内平衡的信号机制
  • 批准号:
    9276991
  • 财政年份:
    2017
  • 资助金额:
    $ 4.9万
  • 项目类别:
Signaling mechanisms that detect stress and maintain homeostasis
检测压力和维持体内平衡的信号机制
  • 批准号:
    10406571
  • 财政年份:
    2017
  • 资助金额:
    $ 4.9万
  • 项目类别:
Regulation of SKN-1/Nrf functions by germline stem cells
生殖干细胞对 SKN-1/Nrf 功能的调节
  • 批准号:
    8582847
  • 财政年份:
    2013
  • 资助金额:
    $ 4.9万
  • 项目类别:
Regulation of SKN-1/Nrf functions by germline stem cells
生殖干细胞对 SKN-1/Nrf 功能的调节
  • 批准号:
    8716631
  • 财政年份:
    2013
  • 资助金额:
    $ 4.9万
  • 项目类别:
Regulation of C. elegans SKN-1/Nrf activity by the unfolded protein response
通过未折叠蛋白反应调节线虫 SKN-1/Nrf 活性
  • 批准号:
    8726427
  • 财政年份:
    2012
  • 资助金额:
    $ 4.9万
  • 项目类别:

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