A novel implementation and social network strategy for acute pulmonary illnesses

急性肺部疾病的新型实施和社交网络策略

基本信息

批准号：
8487124
负责人：
Curtis H. Weiss
金额：
$ 14.21万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-08-05 至 2018-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8487124
关键词：
Accountability Acute Acute Lung Injury Acute respiratory failure Address Adopted Adoption Adult Respiratory Distress Syndrome Adverse effects Attitude Award Bioinformatics Breathing Clinical Sciences Clinical Trials Community Hospitals Complex Critical Care Data Collection Development Plans Diagnosis Disease Electronic Health Record Electronics Environmental air flow Evidence based intervention Evidence based practice Failure Feedback Funding Future Goals Grant Guidelines Happiness Health Healthcare Incidence Institutes Institution Internal Medicine Intervention K-Series Research Career Programs Knowledge Learning Link Lung Lung diseases Mechanical ventilation Medical Medicine Mentors Mentorship Methods Modeling Morbidity - disease rate Nurses Outcome Pathway Analysis Patient Care Patients Physicians Pneumonia Positioning Attribute Procedures Process Protocols documentation Provider Reporting Research Research Infrastructure Research Personnel Science Scientist Site Social Network Surveys System Techniques Testing Tidal Volume Translating Translational Research United States National Institutes of Health Universities Ventilator Weaning awake base career career development clinical infrastructure clinical practice clinical research site design electronic data evidence base implementation science improved innovation meetings mortality multidisciplinary novel patient oriented research programs public health relevance research study respiratory skills success tool treatment as usual

项目摘要

DESCRIPTION (provided by applicant): This career development award will provide Dr. Curtis Weiss the opportunity to develop as an independent researcher of translating research into clinical practice using implementation science and complex network analysis, and to improve the care of patients with acute pulmonary diseases. The current paradigm of implementation is limited because of an ineffective system of translating evidence-based innovations into clinician practice and a lack of understanding about how clinicians learn about and adopt new therapies. Dr. Weiss will use this award to enhance his existing skills with new skills in implementation science and complex network analysis. These skills will allow him to investigate new implementation methods and a better model of how clinicians learn about and adopt evidence-based innovations. He will achieve these career goals through a career development plan that consists of formal coursework, intensive mentorship, and patient-oriented research. His primary mentor is Dr. David Baker, an expert in implementation science with multiple active NIH grants and an outstanding record of mentoring. His co-mentors include experts in implementation science (Dr. Stephen Persell), complex network analysis (Dr. Luis Amaral, a Howard Hughes Medical Institute Early Career Scientist), and ALI, acute respiratory failure, and critical care outcomes (Dr. Richard Wunderink). This will be accomplished at Northwestern University and collaborating clinical sites. Northwestern provides dedicated support from the Division of Pulmonary and Critical Care Medicine and Department of Internal Medicine; 2) his multidisciplinary team of mentors; 3) numerous courses and professional interactions relevant to his career development, including the Northwestern Clinical and Translational Sciences Institute and the Northwestern Institute on Complex Systems; 4) research infrastructure that includes bioinformatics support to design and implement an electronic health record intervention, as well as an institutional electronic data collection program and biostatistical support; and 5) extensive clinical infrastructure. Dr. Weiss with 1) The overall purpose of the research strategy is to use implementation science and complex network analysis to investigate a comprehensive strategy that implements lung protective ventilation and Awake and Breathing Controlled (ABC) weaning, improving the care of patients with acute lung injury (ALI) and acute respiratory failure, respectively. The study will be conducted at one academic and several community hospitals. Specific Aim One will determine the current rate of utilization of these two therapies and link these rates with physician, nurse, and respiratory therapist (provider) knowledge and attitudes about these therapies. Specific Aim Two will use complex network analysis to identify provider opinion leaders at each institution. Specific Aim Three will be a clinical trial that determines whether a multi-faceted, multidisciplinary intervention comprised of opinion leader learning collaboratives, electronic alerts and reminders, and audit and feedback increases implementation rates of low tidal volume ventilation and ABC weaning compared to usual care.

描述（由申请人提供）：该职业发展奖将为Curtis Weiss博士提供开发的机会，成为使用实施科学和复杂网络分析将研究转化为临床实践的独立研究人员，并改善急性肺部疾病患者的护理。目前的实施范式受到限制，因为将基于证据的创新转化为临床医生实践的系统无效，并且对临床医生如何学习和采用新疗法缺乏了解。魏斯博士将使用该奖项来增强他的现有技能，并在实施科学和复杂网络分析方面具有新的技能。这些技能将使他能够调查新的实施方法，并更好地了解临床医生如何学习和采用基于证据的创新。他将通过一项职业发展计划实现这些职业目标，该计划包括正式的课程，密集的指导和面向患者的研究。他的主要导师是戴维·贝克（David Baker）博士，他是实施科学专家，拥有多项活跃的NIH赠款和出色的指导记录。他的委托人包括实施科学专家（Stephen Persell博士），复杂的网络分析（Luis Amaral博士，Howard Hughes医学研究所早期职业科学家）和Ali，急性呼吸道失败和重症监护效果（Richard Wunderink博士）。这将在西北大学和合作临床站点完成。西北航空提供了肺和重症监护医学和内科系的专门支持； 2）他的多学科导师团队； 3）与他的职业发展有关的许多课程和专业互动，包括西北临床和翻译科学学院以及复杂系统的西北学院； 4）包括生物信息学支持的研究基础设施，以设计和实施电子健康记录干预，以及机构电子数据收集计划和生物统计学支持； 5）广泛临床基础设施。 Weiss博士具有1）研究策略的总体目的是使用实施科学和复杂的网络分析来研究一项综合策略，该策略实现了肺部保护性通风，清醒和呼吸控制（ABC）断奶，分别改善了急性肺损伤（ALI）和急性呼吸衰竭患者的护理。该研究将在一家学术和几家社区医院进行。具体目标将确定这两种疗法的当前利用率，并将这些率与医师，护士和呼吸治疗师（提供者）的知识和对这些疗法的态度联系起来。具体目标两个将使用复杂的网络分析来识别每个机构的提供者意见领导者。具体目标三将是一项临床试验，该试验确定了由意见领导者学习合作，电子警报和提醒的多方面，多学科干预措施，以及与通常的护理相比，审计和反馈会增加潮汐量低的通风和ABC断奶的实施率。