Implementation of a pancreas knowledgebase

胰腺知识库的实施

• 批准号: 8231804
• 负责人: JOHN A WILLIAMS
• 金额: $ 4.85万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-15 至 2015-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8231804
• 关键词: Affect; American; Antibodies; Area; Bioinformatics; Biology; Book Chapters; Cellular Structures; Communities; Copyright; Country; Data Security; Development; Directories; Disease; Electronics; Exocrine pancreas; Foundations; Funding; Future; General Population; Health; Individual; Internet; Joints; Knowledge; Libraries; Link; Maintenance; Malignant neoplasm of pancreas; Medicine; Michigan; Mus; Names; Occupations; Pancreas; Pancreatic Diseases; Pancreatitis; Pathology; Pathway interactions; Peer Review; Printing; Procedures; PubMed; Publications; Published Comment; Published Directory; Reading; Request for Applications; Request for Proposals; Research; Research Methodology; Research Personnel; Resources; Schools; Site; Societies; Source; Structure; Surveys; System; Universities; Update; Viral Vector; Work; cell type; cost; data integrity; design; digital; editorial; interest; journal article; knowledge base; meetings; member; tool; web page

DESCRIPTION (provided by applicant): This proposal requests support to construct and implement an electronic resource for information on the exocrine pancreas. This pancreas knowledge base will be called "The Pancreapedia". It is designed to compile and curate knowledge on the exocrine pancreas, its component cell types and its diseases including pancreatitis and pancreatic cancer. It will also encourage new research and promote sharing of methods and research tools. It will contain six major divisions: Reviews, Pathways, Molecule Pages, Cell Structure, Research Tools, and People (Directory, community bulletin board). Content will be divided into "Entries" and "Posts". Entries will be invited or submitted and managed by Editors and an Editorial Board that will carry out peer review. After acceptance, staff will format and mount the finished copy which will be accompanied by a version number, date and digital object identifier (DOI). Material will be hyperlinked to other relevant areas in the site and to sites outside such as PubMed and NCBI. Material can be updated when ever appropriate but when content is changed it will be given a new date and version number. Posts will be entered directly onto a structured web page by individuals who have registered as members and will include Directory Listings, Research Tools (mouse lines, viral vectors, antibodies) and Comments. Comments can be made on all entries and will be accompanied by the commenter's name and picture. The site is constructed using Drupal as the content management system with the aim of minimizing the work of putting up new content. It will be mounted on a server at the University of Michigan Library (MPublishing) which will be the Publisher and responsible for data security and integrity. All content will be open access with the copyright remaining with the author. After establishment of the resource funds to cover the cost of maintenance and putting up new content will come from The American Pancreatic Association and other organizations (Societies and Foundations) interested in pancreatic research.

描述（由申请人提供）：该提案请求支持以构建和实施电子资源以获取有关外分泌胰腺的信息。这个胰腺知识库将被称为“ pancreapedia”。它旨在编译和策划有关外分泌胰腺，其组成细胞类型及其疾病（包括胰腺炎和胰腺癌）的知识。它还将鼓励新的研究并促进方法和研究工具的共享。它将包含六个主要部门：评论，途径，分子页，细胞结构，研究工具和人员（目录，社区公告委员会）。内容将分为“条目”和“帖子”。将邀请或提交和管理条目，并由编辑委员会和编辑委员会进行同行评审。接受后，工作人员将格式化并安装成品副本，该副本将附有版本编号，日期和数字对象标识符（DOI）。材料将超级链接到该站点的其他相关区域以及PubMed和NCBI之类的外部。可以在适当的情况下更新材料，但是在更改内容时，将为新的日期和版本编号提供。帖子将由注册为成员的个人直接输入结构化的网页，其中包括目录列表，研究工具（鼠标线，病毒矢量，抗体）和评论。可以在所有条目上发表评论，并伴随评论者的姓名和图片。该网站是使用Drupal作为内容管理系统构建的，目的是最大程度地减少提出新内容的工作。它将安装在密歇根大学图书馆（MPUBLISHISH）的服务器上，该服务器将成为发布者，并负责数据安全和完整性。所有内容将与作者剩下的版权进行开放访问。建立资源资金以支付维护成本并提出新内容后，将来自美国胰腺协会和其他对胰腺研究感兴趣的组织（社会和基金会）。