Training New Investigators in Neuroimaging and in the Neuropsychiatry of Movement

培训神经影像学和运动神经精神病学方面的新研究人员

基本信息

批准号：
8197080
负责人：
KEVIN J BLACK
金额：
$ 16.49万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-12-01 至 2014-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8197080
关键词：
Adult Affect Agonist Akathisia American Anxiety Area Award Brain Brain region Carbidopa Child Psychiatry Clinical Cognitive Collaborations Commit Communities Comorbidity Consult Consultations Core-Binding Factor Data Data Analyses Development Diagnosis Diagnostic Disinhibition Doctor of Medicine Dopamine Dopamine Agonists Dopamine Receptor Dose Dyskinetic syndrome Epidemiologic Studies Epidemiology Experimental Designs Faculty Fellowship Functional Magnetic Resonance Imaging Funding Future Genetic Gilles de la Tourette syndrome Grant Health Image Infusion procedures Inpatients Institution Interview Investigation K-Series Research Career Programs Levodopa MRI Scans Medial Mentors Mentorship Methods Mid-Career Clinical Scientist Award (K24)Midcareer Investigator Award in Patient-Oriented Research Moods Motor Movement Movement Disorders National Institute of Mental Health Neurosciences Research Parietal Lobe Parkinson Disease Patients Pediatric Neurology Performance Perfusion Pharmacology Pilot Projects Placebo Effect Plasma Positron-Emission Tomography Postdoctoral Fellow Psychiatric Diagnosis Psychiatrist Psychiatry Publishing REM Sleep Behavior Disorder Receptor Activation Recording of previous events Research Research Activity Research Personnel Research Support Residencies Rewards Role Sampling Scanning Severities Short-Term Memory Signal Transduction Structure of subthalamic nucleus Students Symptoms System Testing Thalamic structure Time Training Training Activity Validity and Reliability Work career clinical application depressive symptoms endophenotype experience follow-up frontal lobe improved medical schools neuroimaging neuropsychiatry patient oriented research programs response single episode major depressive disorder

项目摘要

DESCRIPTION (provided by applicant): This application for a Midcareer Investigator Award in Patient-Oriented Research (K24) is planned to allow the PI to devote 50% effort to the mentoring and research activities described. The PI is a board-certified neuropsychiatrist who completed a two-year movement disorders and neuroimaging fellowship after psychiatry residency. He has contributed new neuroimaging methods and applied them to neuropsychiatric aspects of Parkinson disease and TS. His current research includes studies in both these areas, but this application focuses on the PI's research into Tourette syndrome (TS). This includes ongoing neuroimaging studies funded by NIMH and the Tourette Syndrome Association, and new TS imaging studies are proposed for this application. The new studies build on the PI's past research, follow up on exciting leads from recently published TS research, and are planned to further develop a coordinated research program on TS in collaboration with colleagues from child neurology and child psychiatry. The PI has mentored over 40 young trainees over the years, many of them for brief summer or semester stints, but some for longer terms. In the past 3 years, 2 of the PI's longer-term clinical trainees (a psychiatry resident and a clinical neuropsychologist post-doc) have won the American Neuropsychiatric Association's Young Investigator Award for research done in his lab and for their overall career potential. The PI has now identified new M.D. research fellows and students whose training will be enhanced by additional time for the specific mentorship activities proposed herein. The institution is well known as a vibrant center for neuroscience research, and its recently awarded CTSA grant components will further support the training and research activities in this proposal. The department has committed to free the PI from his administrative duties with the medical school core psychiatry clerkship and from inpatient or consultation-liaison clinical duties in exchange for the mentorship and patient-oriented research opportunities that this K24 award will support. In short, the applicant's mentoring experience, research contributions, and near-future plans for research on TS have all arrived at the perfect moment for appropriate support from the K24.

描述（由申请人提供）：计划在以患者为导向的研究（K24）中获得中级护理研究者奖（K24），以允许PI将50％的努力用于所述的指导和研究活动。 PI是一名经过董事会认证的神经精神科医生，在精神病学居住后完成了两年的运动障碍和神经影像学研究金。他贡献了新的神经影像学方法，并将其应用于帕金森氏病和TS的神经精神科方面。他目前的研究包括在这两个领域的研究，但该应用程序侧重于PI对Tourette综合征（TS）的研究。这包括由NIMH和Tourette综合征协会资助的正在进行的神经影像学研究，并为此应用提出了新的TS成像研究。新的研究以Pi的过去研究为基础，跟进了最近发表的TS研究的令人兴奋的潜在客户，并计划进一步与儿童神经病学和儿童精神病学的同事合作开发有关TS的协调研究计划。多年来，PI指导了40多名年轻学员，其中许多人在短暂的夏季或学期任职，但有些则更长。在过去的3年中，PI的2名长期临床学员（精神病学居民和DOC临床神经心理学家）赢得了美国神经精神病学协会在实验室中获得的研究和整体职业潜力的研究奖。 PI现在已经确定了新的医学博士研究研究员和学生，他们的培训将通过此处提出的特定指导活动的额外时间来增强培训。该机构是一个充满活力的神经科学研究中心，其最近授予的CTSA赠款组件将进一步支持该提案中的培训和研究活动。该部门已致力于将PI从医学院的核心精神病学文员和咨询或咨询服务临床职责中解放出他的行政职责，以换取该K24奖将支持的指导和面向患者的研究机会。简而言之，申请人的指导经验，研究贡献和TS研究的近乎预测计划都到了，以获得K24的适当支持的最佳时机。