METAPHASE SPINDLE PROTEOME

中期纺锤体蛋白质组

• 批准号: 8365842
• 负责人: Ahna Renee Skop
• 金额: $ 1.28万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365842
• 关键词: Biology; Cell Cycle Stage; Cell division; Cells; Cytokinesis; Funding; Fungal Genome; Goals; Grant; Lead; National Center for Research Resources; Principal Investigator; Proteins; Proteomics; Research; Research Infrastructure; Resources; Source; Staging; Techniques; United States National Institutes of Health; comparative genomics; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Our goal is to understand the mechanisms of cytokinesis. We are using proteomic and comparative genomic techniques to identify proteins that are required during specific cell cycle stages. Analyzing protein composition of different cell stages may lead to better understanding of the mechanism of cell division by pinpointing proteins specific to particular cell cycle stage.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 我们的目标是了解胞质分裂的机制。 我们正在使用蛋白质组学和比较基因组技术来识别特定细胞周期阶段所需的蛋白质。分析不同细胞阶段的蛋白质组成可以通过精确定位特定细胞周期阶段的蛋白质来更好地理解细胞分裂的机制。