Project 7: Chloro-Organic Degradation by Nanosized Metallic Systems and by Chelat

项目 7：纳米金属系统和 Chelat 降解氯有机物

• 批准号: 8249964
• 负责人: Dibakar Bhattacharyya
• 金额: $ 24.23万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8249964
• 关键词: Advanced Development; Anions; Carbon; Characteristics; Chelating Agents; Chemicals; Chlorine; Development; Educational workshop; Effectiveness; Environment; Enzymes; Equilibrium; Flushing; Foundations; Free Radicals; Future; Generations; Glucose; Health Benefit; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Immobilization; In Situ; Iron; Iron Chelating Agents; Kinetics; Lead; Life; Maps; Membrane; Metals; Methods; Modeling; Monitor; Morphology; Nanostructures; Nanotechnology; Nanotubes; National Institute of Environmental Health Sciences; Natural regeneration; Parents; Pathway interactions; Phase; Phenols; Pollution; Polychlorinated Biphenyls; Polymers; Production; Property; Reaction; Reagent; Research; Roentgen Rays; Role; Salts; Sampling; Site; Soil; Solvents; Spectrum Analysis; Structure; Superoxides; Surface; System; Techniques; Technology; Testing; Toxic effect; Trichloroethylene; Vascular Endothelial Cell; Vinyl Chloride; Water; Work; base; biodegradable product; catalyst; cost effective; dechlorination; diphenyl; enzyme immobilization; flexibility; gluconate; glucose oxidase; improved; innovation; membrane assembly; nanoparticle; nanosized; nanostructured; novel strategies; nutrition; operation; organic acid; oxidation; particle; pollutant; reaction rate; remediation; superfund chemical; superfund site; surfactant; technology development

Chlorinated organics bring toxicity from water, soil, and sediment phases, and exert a cumulative, deleterious effect on the environment. Various Superfund sites contain mixtures of RGBs, chloroethylenes, and other compounds. The degradation of of chloro-organics to nontoxic, non-chlorinated, and easily biodegradable products will require integrated approaches involving "combined" (reductive and oxidative) remediation technologies. Our proposed approach to use combined technologies should lead to significant improvement over current remediation practices by the elimination of the production of chloro-organic intermediates. Our research will focus on the degradation of selected RGBs, TCE, and RGB mixtures. A thorough understanding of the reaction kinetics for both steps (reductive and oxidative), the potential role of surfactants, and material (such as doping catalyst metals, chelates) characteristics will be important for the integration of the steps. The approaches taken for reductive dechlorination by bimetallic nanoparticles in polymer media and nanotubes will allow the development of highly controlled structures for high reactivity and stability. The proposed technology will have a significant impact on the role of nanostructured materials and hydroxyl radical /superoxide radical anion reaction pathway in the environmental field for current and future needs. The technique for potential on-site generation of hydrogen peroxide and gluconic acid (iron chelate) provides enzyme (glucose oxidase) immobilization using an innovative approach of layer- by-layer assembled membranes, and this should enhance application opportunities in various Superfund sites. Kinetic modeling of both oxidative and reductive systems should establish an excellent foundation for fundamental understanding of bimetallic nanotechnology-based systems and for chelate-modified hydroxyl/superoxide radical-based reactions. Another important aspect of this proposal is that pollutant toxicity will be reduced significantly for both the dechlorination step and the combined reaction systems. Relevance: The proposed research is expected to have significant positive impact on pollution remediation through flexible dechlorination technology developments with significant reduction of material usage, and highly improved health benefits through toxicity reduction.

氯化有机物带来水，土壤和沉积物阶段的毒性，并发挥累积性， 对环境的有害影响。各种超级基金地点包含RGB，氯乙烯的混合物， 和其他化合物。氯化物质的降解为无毒，非氯化和容易 可生物降解的产品将需要涉及“合并”（还原性和氧化）的集成方法 修复技术。我们提出的使用合并技术的方法应导致重大 通过消除氯仿的产生来改善当前补救实践 中间人。我们的研究将集中于选定的RGB，TCE和RGB混合物的降解。一个 对这两个步骤的反应动力学的全面了解（还原性和氧化），这是潜在的作用 表面活性剂和材料（例如掺杂催化剂金属，螯合物）的特性对 步骤的集成。双金属纳米颗粒在 聚合物培养基和纳米管将允许开发高度反应性的高度控制结构 和稳定性。拟议的技术将对纳米结构材料的作用产生重大影响 和羟基自由基 /超氧化物自由基阴离子反应途径在环境场中的电流和 未来需求。潜在现场生成过氧化氢和葡萄糖酸的技术（铁） 螯合物）使用层 - 副层的创新方法提供固定酶（葡萄糖氧化酶） 组装的膜，这应该增加各种超级基金站点的应用机会。 氧化和还原系统的动力学建模应为 对基于双金属纳米技术的系统的基本理解和用于螯合物修饰的系统 羟基/超氧化物自由基反应。该提案的另一个重要方面是污染物 脱氯化步骤和组合反应系统都将显着降低毒性。 相关性：预计拟议的研究将对污染修复产生重大积极影响 通过灵活的脱氯化技术开发，并大大降低了材料的使用和 通过降低毒性，高度改善的健康益处。