SUPRAGENOME ANALYSES OF HUMAN BACTERIAL PATHOGENS

人类细菌病原体的超基因组分析

• 批准号: 7956178
• 负责人: Garth D. Ehrlich
• 金额: $ 0.08万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956178
• 关键词: Biomedical Research; Computer Retrieval of Information on Scientific Projects Database; Data; Funding; Genes; Genome; Goals; Grant; High Performance Computing; Human; Institution; Modeling; Proteins; Research; Research Personnel; Resources; Source; United States National Institutes of Health; computer studies; pathogen

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this computational study is to facilitate the quantitative delineation of the supragenome of important human bacterial pathogens using the finite supragenome model of Hogg et al. (http://genomebiology.com/2007/8/6/R103). We seek to perform all-against-all FASTA and TFASTA searches using the CDS gene sets (and their protein products) of the genomes from each available strain (for which data is available) of a given species of human bacterial pathogen

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 这项计算研究的目标是利用 Hogg 等人的有限超基因组模型，促进对重要人类细菌病原体的超基因组的定量描述。 （http://genomebiology.com/2007/8/6/R103）。我们寻求使用给定人类细菌病原体物种的每个可用菌株（其数据可用）的基因组的 CDS 基因集（及其蛋白质产物）进行全面的 FASTA 和 TFASTA 搜索