B-CLL SUBGROUPS: MATURATION STAGE & GENE EXPRESSION

B-CLL 亚群：成熟阶段

• 批准号: 7951906
• 负责人: Nicholas Chiorazzi
• 金额: $ 2.72万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951906
• 关键词: Categories; Chronic Lymphocytic Leukemia; Clinical; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Disease; Funding; Gene Expression; Gene Mutation; Grant; Institution; Patients; Research; Research Personnel; Resources; Source; Staging; Subgroup; United States National Institutes of Health; base; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Recent studies have found that the disease B-type chronic lymphocytic leukemia (B-CLL) can be divided into two subgroups based on lg V gene mutation status and CD 38 expression. The patients in these two groups follow different clinical courses. This proposal is designed to understand more precisely how these two broad categories of B-CLL cases differ.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 最近的研究发现，B型慢性淋巴细胞白血病（B-CLL）可根据lg V基因突变状态和CD 38表达分为两个亚组。这两组患者的临床病程不同。 该提案旨在更准确地了解这两大类 B-CLL 病例有何不同。