Social Determinants Predicting Trajectories of HIV with Recent Latina Immigrants

预测近期拉丁裔移民艾滋病毒感染轨迹的社会决定因素

• 批准号: 8352471
• 负责人: Frank R Dillon
• 金额: $ 19.74万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-12-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8352471
• 关键词: 21 year old; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Adult; Age; Alcohol or Other Drugs use; Alcohols; Attenuated; Blood; Cause of Death; Chronic Disease; Communities; Data; Daughter; Development; Diagnosis; Disadvantaged; Drug Addiction; Drug abuse; Factor Analysis; Fatal Outcome; Fathers; Florida; Funding; Goals; HIV; Health; Health Services; Health Services Accessibility; Healthcare; Hepatitis; High Risk Woman; Ice; Immigrant; Incidence; Individual; Infection; Instruction; International; Intervention; Interview; Laboratories; Latina; Latino; Lead; Longitudinal Studies; Mental disorders; Modeling; Mothers; Outcome; Parents; Persons; Pharmaceutical Preparations; Prevention program; Prevention strategy; Preventive Intervention; Process; Questionnaires; Research; Resources; Risk; Risk Behaviors; Risk Factors; Saliva; Screening procedure; Services; Severities; Social Policies; Substance Use Disorder; System; Testing; Triiodothyronine; United States; Universities; Urine; Woman; base; community based participatory research; community organizations; follow-up; high risk; high risk behavior; indexing; innovation; instrument; overdose death; peer; resilience; social; sound

This proposed community-based participatory research subproject is part of our P20 competitive renewal application of the NIMHD-funded Center for Substance Use and AIDS Research on Latinos in the United States (C-SALUD) at Florida International University (FIU). The proposed longitudinal study consists of 4-annual assessments of recent Latina immigrants (N=600; ages of 18-23). By partnering with local community-based organizations, our multi-disciplinary research team will: (1) elucidate culturally relevant antecedent social determinants of liability (consisting of individual, cultural, interpersonal and community/institutional determinants collectively referred to as social determinants) which predict HIV/AIDS risk behaviors (HIVR), concomitant substance use severity (SUS), HIV/AIDS diagnoses, substance use disorders (SUDs) and access to health care resources (HCR), (2) determine the moderating effects of dyadic attachments (daughter-father, daughter-mother, daughter-peers, daughter-romantic partner) on the relationship between adverse social determinants and early adult trajectories of HIV/AIDS risk behaviors and SUS, (3) clinically validate outcomes with laboratory tests (saliva, urine and blood) for alcohol plus 9-drug classes, HIV-EIA and STDs and (4) create a psychometrically sound and culturally relevant screening instrument derived from the obtained results (Latina Screening Index of Risk and Resilience-LaSIRR) which may be employed to identify recent Latina immigrants at high risk to succumb to HIV/AIDS and SUDs. Longitudinal statistical analyses will capture dynamic system interactions between change processes and causal networks to elucidate interactions among the modeled variables across 4-annual waves. Factor analyses will be applied to data obtained at baseline assessment to derive a preliminary LaSIRR to predict HIV and SUD outcomes across 3 follow-up assessments.

这项拟议的基于社区的参与研究副本是我们在美国佛罗里达国际大学（FIU）的NIMHD资助的物质使用中心（C-Salud）的P20竞争性更新应用的一部分。拟议的纵向研究包括对最近拉丁移民的4年评估（n = 600；年龄18-23）。通过与当地社区组织合作，我们的多学科研究团队将：（1）阐明与文化相关的 责任的前期社会决定因素（由个人，文化，人际和社区/机构/机构/机构决定因素共同称为社会决定因素），这些决定因素预测HIV/AIDS风险行为（HIVR）（HIVR），伴随物质的物质使用，严重性（SUS），HIV/AIDS诊断障碍（SUDS）和医疗保健资源（SUDS）（SUDS）（SUDS）（SUDS）（HIDS）（2） （女儿父亲，女母亲，女儿同胞，女儿浪漫伴侣） relationship between adverse social determinants and early adult trajectories of HIV/AIDS risk behaviors and SUS, (3) clinically validate outcomes with laboratory tests (saliva, urine and blood) for alcohol plus 9-drug classes, HIV-EIA and STDs and (4) create a psychometrically sound and culturally relevant screening instrument derived from the obtained results (Latina Screening Index of Risk and Resilience-LaSIRR) which 可以用来识别最近有高风险的拉丁裔移民，屈服于艾滋病毒/艾滋病和泡沫。 纵向统计分析将捕获变化过程和因果网络之间的动态系统相互作用，以阐明4年波浪之间建模变量之间的相互作用。因子分析将应用于在基线评估时获得的数据，以得出初步的LASIRR，以预测3个随访评估中的HIV和SUD结果。