Research Core

研究核心

• 批准号: 8355944
• 负责人: Mandip Singh Sachdeva
• 金额: $ 16.48万
• 依托单位: FLORIDA AGRICULTURAL AND MECHANICAL UNIV
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-16 至 2017-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8355944
• 关键词: Affect; Antineoplastic Agents; Area; Breast Cancer Treatment; Cancer Research Infrastructure; Chemicals; Collaborations; Community Services; Educational workshop; Equipment; Faculty; Federal Government; Florida; Funding; Funding Opportunities; Goals; Grant; Historically Black Colleges and Universities; Lead; Mainstreaming; Malignant Neoplasms; Malignant neoplasm of lung; Minority; Molecular; Outcome; Population; Productivity; Publishing; Research; Research Infrastructure; Research Personnel; Research Training; Resources; Therapeutic Studies; Universities; Writing; anticancer research; cancer therapy; chemotherapeutic agent; innovation; investigator training; malignant breast neoplasm; tumor

The overall goal of this initiative is to strengthen the research infrastructure for cancer research at Florida A&M University through research collaboration in a focused and coordinated effort. Despite significant discovery of chemotherapeutic agents and their mechanisms of action, the need for new chemical entities having new mechanisms of action for the treatment of breast and lung cancer remains high. Therefore, an aggressive exploitation of new anticancer agents/combination and their molecular mechanisms involved in tumor regression are planned through research collaboration. Breast and lung cancer are the most common cancer affecting minority populations and these two cancers hence been chosen to be pursued at FAMU. Furthermore, FAMU has researchers who are performing cutting edge research in these areas and hence can contribute in building a strong infrastructure for other researchers. Another impetus for this activity is to take a step towards remedy for the persistent disparity in the number of minority investigators involved in targeted cancer therapy research. The difficulty in implementing innovative approaches in cancer research at historically black colleges and universities is due to the lack of adequate resources, trained investigators and research infrastructure for breast and lung cancer therapy.

该计划的总体目标是通过重点协调的研究合作，加强佛罗里达农工大学癌症研究的研究基础设施。尽管化疗剂及其作用机制有了重大发现，但对具有新作用机制的新化学实体用于治疗乳腺癌和肺癌的需求仍然很高。因此，计划通过研究合作积极开发新的抗癌药物/组合及其参与肿瘤消退的分子机制。乳腺癌和肺癌是影响少数群体的最常见癌症，因此这两种癌症被选择在 FAMU 进行治疗。 此外，FAMU 拥有在这些领域进行前沿研究的研究人员，因此可以为其他研究人员建立强大的基础设施做出贡献。这项活动的另一个推动力是采取措施纠正参与靶向癌症治疗研究的少数族裔研究人员数量持续存在的差距。历史上在癌症研究中实施创新方法的困难 黑人学院和大学的原因是缺乏足够的资源、训练有素的研究人员和乳腺癌和肺癌治疗的研究基础设施。