COBRE: UID: MOLECULAR & CELLULAR BASIS OF HOST PATHOGEN INTERACTIONS

COBRE：UID：分子

• 批准号: 7959724
• 负责人: Gregory A Bohach
• 金额: $ 72.38万
• 依托单位: UNIVERSITY OF IDAHO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959724
• 关键词: Arts; Binding; Biomedical Research; Cell Separation; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Ensure; Faculty; Funding; Genomics; Goals; Graduate Education; Grant; Human Resources; Idaho; Institution; Investments; Medical Students; Microscopy; Molecular; Pathogenesis; Persons; Positioning Attribute; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Source; United States National Institutes of Health; Universities; base; graduate student; member; microbial; pathogen; programs; structural biology; success

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. By facilitating the building of our personnel and infrastructure bases, COBRE support over the past five years has had a significant impact on research in microbial pathogenesis at the University of Idaho. In addition to two new COBRE-funded investigators added during the initial funding period, our university administration has partnered with the COBRE PI to create four additional tenure-track positions during the past four years. With this new group of talented faculty and the success of our COBRE faculty we have made progress toward establishing the UI as an institution with a nationally recognized biomedical program with a focus on microbial pathogenesis. To build upon this success, we propose four specific aims. Specific Aim 1: Extend the critical mass and expand the scientific diversity of the core group of COBRE co-Investigators. In this aim we propose to add to our existing COBRE team by providing research support for the recently hired faculty members, as well as more established faculty members not currently funded by NIH, and an additional person to be identified. Specific Aim 2: Expand and support COBRE funded core facilities. With COBRE and UI support, we were able to leverage private funding to build several state-of-the-art core facilities, including Structural Biology, Microscopy, Cell Separation, and Genomics Core Facilities. In this proposal, we describe plans to expand and/or support these facilities to ensure that initial investments made by COBRE and the UI efficiently enhance research of COBRE investigators and other biomedical investigators on campus. Specific Aim 3: Enhance the quality and numbers of graduate/medical students to participate in biomedical research. With the documented increase in higher quality graduate students we have been able to recruit since the beginning of the COBRE funding cycle, we will use additional COBRE funds to further enhance our graduate recruiting efforts. This will be done by enhancing stipends, promoting recruitment in the U.S. and internationally, plus interfacing with the Idaho INBRE's "Pipeline to Graduate Education" program. Specific Aim 4: Transition toward self-sustaining biomedical research support from the National Institutes of Health following completion of COBRE funds. This final aim will help to establish the COBRE investigators as independent researchers with the ultimate goal of obtaining long-term program project support from the NIH.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 通过促进人员和基础设施建设，COBRE 在过去五年的支持对爱达荷大学的微生物发病机制研究产生了重大影响。 除了在最初资助期间增加了两名由 COBRE 资助的新研究人员之外，我们的大学管理部门还与 COBRE PI 合作，在过去四年中额外设立了四个终身职位。 凭借这群新的才华横溢的教师队伍以及 COBRE 教师的成功，我们在将 UI 建设成为一个拥有国家认可的生物医学项目、重点研究微生物发病机制的机构方面取得了进展。 为了在这一成功的基础上再接再厉，我们提出了四个具体目标。 具体目标 1：扩大 COBRE 联合研究者核心小组的临界规模并扩大其科学多样性。 为此，我们建议通过为最近聘用的教职人员、目前尚未获得 NIH 资助的更多资深教职人员以及待确定的其他人员提供研究支持，来扩充我们现有的 COBRE 团队。 具体目标 2：扩大和支持 COBRE 资助的核心设施。 在 COBRE 和 UI 的支持下，我们能够利用私人资金建设多个最先进的核心设施，包括结构生物学、显微镜、细胞分离和基因组学核心设施。 在本提案中，我们描述了扩大和/或支持这些设施的计划，以确保 COBRE 和 UI 的初始投资有​​效地加强 COBRE 研究人员和校园内其他生物医学研究人员的研究。 具体目标3：提高研究生/医学生参与生物医学研究的质量和数量。 自 COBRE 资助周期开始以来，随着我们能够招募的更高质量研究生的增加，我们将使用额外的 COBRE 资金来进一步加强我们的毕业生招聘工作。 这将通过增加津贴、促进美国和国际招聘以及与爱达荷州 INBRE 的“研究生教育管道”计划对接来实现。 具体目标 4：在 COBRE 基金完成后，转向美国国立卫生研究院的自我维持生物医学研究支持。 这一最终目标将有助于将 COBRE 研究人员建立为独立研究人员，最终目标是获得 NIH 的长期计划项目支持。