Administrative Core

行政核心

• 批准号: 8299605
• 负责人: RICHARD J. WHITLEY
• 金额: $ 9.81万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8299605
• 关键词: Accounting; Advisory Committees; Alabama; Animal Model; Animal Testing; Basic Science; Biological Models; Cancer Center; Cellular biology; Chicago; Clinical Research; Clinical Trials; Conduct Clinical Trials; Consultations; Engineering; Ensure; Expenditure; Glioma; Goals; Human; In Vitro; Individual; Institution; Instruction; Leadership; Letters; Malignant Glioma; Methodology; Molecular Biology; Molecular Virology; Monitor; National Cancer Institute; Participant; Preparation; Principal Investigator; Production; Program Research Project Grants; Research Activity; Research Personnel; Research Project Grants; Research Support; Safety; Scientist; Screening procedure; Services; Shapes; Simplexvirus; Therapeutic; Toxic effect; Translations; Universities; Viral; Virus; Work; base; design; implementation research; medical schools; meetings; oncolysis; operation; preclinical evaluation; programs

Core A Administrative Core The Administrative Core is under the Direction of the Program Director, Dr. Richard J. Whitiey. As the responsible Principal Investigator for the Program Project Grant, he will provide the scientiflc and administrative leadership for the overall program. He will be assisted in these tasks by Drs. G. Yancey Gillespie and James M. Markert, Program Co-Directors. Together, these Administrative Core Leaders will provide centralized management support, and collaborative research support for all research projects of this two-institution Program Project Grant. The purpose of this Core is to provide the administrative framework to facilitate the rapid and expeditious translation of our basic science advances into therapeutic opportunities for humans. The interdigitation of molecular virology, cellular biology. In vitro screening, animal model studies, and other facilitating work will be coordinated by the Administrative Core. Administrative funcflons also include oversight of operations and budgetary issues for all Program Project investigators and Core Leaders. Quarterly meetings with all of the Project and Core leaders will be organized and coordinated to ensure that the research activities proceed in a timely fashion and that all program participants have an informal forum to shape and focus the direction of the research activities. These meetings will also enhance the integration of project and core activities with each other, based on priorities that are identifled from results presented at each meeting. The Administrative Core will coordinate an annual meeting with the External Advisory Committee which will evaluate the progress of the individual Program projects and the services provided by the Cores. The External Advisory Committee is compised of 3 outstanding scientists. Dr. Thomas Shenk, virologist, Dr. Darell D. Bigner, glioma expert and Dr. Robert Martuza, a leader in viral oncolysis and clinical studies. All efforts will be focused on the flmely translation of the flndings on molecular biology of herpes simplex viruses and the cellular biology of the virus-host relation to the treatment of human malignant gliomas. This program project grant has the full support of the University of Alabama at Birmingham and the University of Chicago. Letters of support appear from Drs. C Garrison (President, UAB), E Capiluto (Provost, UAB), R Rich (Dean, School of Medicine, UAB), E Partridge (Director, UAB Comprehensvive Cancer Center), S Stagno (Chair, Department of Pediatircs) and M. LeBeau (Director, The University of Chicago Cancer Center). RELEVANCE (See instructions):

核心行政核心 行政核心在计划主任理查德·J·怀特（Richard J. Whitiey）的指导下。作为 负责计划项目赠款的首席研究员，他将提供Scientiflc和 整个计划的行政领导。 Drs将协助他完成这些任务。 G. Yancey Gillespie和James M. Markert，计划联合导演。这些行政核心领导者在一起将 为所有研究项目提供集中的管理支持和协作研究支持 两机构计划项目赠款。该核心的目的是提供管理框架 促进我们将基础科学发展迅速转化为治疗机会 对于人类。分子病毒学，细胞生物学的互插。体外筛查，动物模型 研究和其他促进工作将由行政核心协调。行政功能 还包括对所有计​​划项目调查人员和核心的操作和预算问题的监督 领导者。与所有项目和核心领导者的季度会议将进行组织和协调 确保研究活动及时进行，并且所有计划参与者都有 非正式论坛，以塑造和集中研究活动的方向。这些会议也将增强 基于从中识别的优先级，项目和核心活动相互集成 每次会议上都会提出结果。行政核心将与 外部咨询委员会将评估个别计划项目的进度和 核心提供的服务。外部咨询委员会由3位杰出科学家组成。 病毒学家，Darell D. Bigner博士，Glioma Expert和Robert Martuza博士 分解和临床研究。所有努力都将集中于分子上的flndings的flmely翻译 单纯疱疹病毒的生物学和与人类治疗的病毒宿主关系的细胞生物学 恶性神经胶质瘤。该计划项目赠款得到了阿拉巴马大学的全部支持 伯明翰和芝加哥大学。 Drs的支持信出现。 C驻军（总裁， UAB），E Capiluto（UAB教务长），R Rich（Dean，医学院，UAB），E Partridge（UAB主任 综合癌症中心），S Stagno（Pedircs系主任）和M. Lebeau（主任 芝加哥大学癌症中心）。 相关性（请参阅说明）：