Informing Latinas About Medications To Reduce Risk For Breast Cancer

告知拉丁裔有关降低乳腺癌风险的药物

• 批准号: 8009542
• 负责人: Marielena Lara
• 金额: $ 148.71万
• 依托单位: RAND CORPORATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2013-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8009542
• 关键词: Informing; Latinas; About; Medications; Reduce

DESCRIPTION (provided by applicant): Significant disparities exist between the prevention and treatment of breast cancer among Latinas and non-Latina white women. An important factor appears to be the difference in access to evidence-based health information between these groups of women. Dissemination of language-, literacy-, and culturally appropriate prevention and treatment messages could reduce disparities in access to evidenced-based health information and preventive care for Latinas at risk for breast cancer. RAND Health, in collaboration with Olive View-UCLA Medical Center (OVMC), a Los Angeles County Department of Health Services hospital, proposes to develop and conduct a pilot evaluation of three alternative strategies to communicate patient-targeted messages related to the CER, "Comparative Effectiveness of Medications to Reduce Risk for Primary Breast Cancer in Women." The overall aim is to increase the use, impact, and implementation of the recommendations of this CER by adapting and testing innovative alternative strategies among Spanish-speaking women at risk for breast cancer. No consumer-oriented materials currently exist for this CER. This proposal has three specific aims: 1. To conduct formative research to develop language-, literacy-, culturally-, and content-appropriate evidence-based patient-oriented messages for the chosen CER. 2. To develop and pilot test the efficacy of three alternative prototypes (e.g., print media, community health worker, computer delivery) for the delivery of the messages in Spanish-speaking women. 3. To develop, in collaboration with AHRQ and other stakeholders, a plan to disseminate the results to promote the effectiveness and impact of the CER recommendations among Latina women at risk. To balance consumer-, clinical, and evidence-based perspectives, the project will employ a community advisory board of stakeholders, key informant interviews, and focus groups to assist in identifying and "translating" the key messages, identifying the optimal dissemination venues, and recruiting a population of high-risk women to test the vehicles. We define translation as adapting the language, literacy level, and cultural focus of the CER's evidenced-based recommendations to target the intended audience. The available dissemination materials for this CER topic are highly technical. Thus, for this initial project, we concentrate on evaluating the relative efficacy of the translated strategies using a multi-arm randomized control trial. An important part of our project will be to develop a dissemination plan that considers alternatives for scaling up of the intervention(s) that we find to be efficacious for future evaluation of their effectiveness in the real world. RAND Health has assembled an exceptional project team with skills and experience in the evidence review process, breast cancer prevention and treatment, health communication, bilingual and bicultural implementation and evaluation methods, as well as direct experience with the population of interest. PUBLIC HEALTH RELEVANCE: Lack of language-, literacy-, and culturally-appropriate evidenced-based information contributes to disparities in breast cancer health care and health between Latinas and non-Latina white women. The proposed project will pilot and compare three evidence- based patient-oriented educational prototypes targeting Latinas, for a potentially life- saving preventive treatment, and using alternative modes of delivery (print media, community health worker, computer delivery).

描述（由申请人提供）：拉丁裔和非拉丁裔白人女性的乳腺癌预防和治疗存在显着差异。一个重要因素似乎是这些妇女群体在获取循证健康信息方面存在差异。传播语言、识字和文化上适当的预防和治疗信息可以减少有乳腺癌风险的拉丁裔在获得循证健康信息和预防性护理方面的差异。兰德健康公司与洛杉矶县卫生服务部医院 Olive View-UCLA 医疗中心 (OVMC) 合作，提议开发并开展对三种替代策略的试点评估，以传达与 CER 相关的针对患者的信息，“降低女性原发性乳腺癌风险的药物的比较有效性。”总体目标是通过在有乳腺癌风险的西班牙语女性中调整和测试创新的替代策略，提高本 CER 建议的使用、影响和实施。目前不存在适用于此 CER 的面向消费者的材料。该提案具有三个具体目标： 1. 进行形成性研究，为所选 CER 开发语言、读写能力、文化和内容适当的、基于证据的、以患者为导向的信息。 2. 开发并试点测试三种替代原型（例如印刷媒体、社区卫生工作者、计算机传递）向讲西班牙语的妇女传递信息的功效。 3. 与 AHRQ 和其他利益攸关方合作制定一项计划，传播结果，以提高 CER 建议对面临风险的拉丁裔妇女的有效性和影响。为了平衡消费者、临床和基于证据的观点，该项目将聘请利益相关者组成的社区咨询委员会、关键知情者访谈和焦点小组来协助识别和“翻译”关键信息，确定最佳传播场所，并招募一群高危女性来测试车辆。我们将翻译定义为调整 CER 循证建议的语言、读写水平和文化焦点，以瞄准目标受众。该 CER 主题的可用传播材料技术性很强。因此，对于这个初始项目，我们专注于使用多臂随机对照试验来评估翻译策略的相对功效。我们项目的一个重要部分将是制定一项传播计划，考虑扩大干预措施的替代方案，我们发现这些干预措施对于未来评估其在现实世界中的有效性是有效的。兰德健康公司组建了一支出色的项目团队，在证据审查过程、乳腺癌预防和治疗、健康传播、双语和双文化实施和评估方法以及与感兴趣人群的直接接触方面拥有技能和经验。 公共卫生相关性：缺乏语言、读写能力和文化上适当的循证信息导致拉丁裔和非拉丁裔白人女性在乳腺癌医疗保健和健康方面存在差异。拟议的项目将试点和比较三种针对拉丁裔的以证据为基础、以患者为导向的教育原型，以寻求一种可能挽救生命的预防性治疗，并使用替代的交付模式（印刷媒体、社区卫生工作者、计算机交付）。

项目成果

Taking Care of Yourself and Your Risk for Breast Cancer (CUIDARSE): A Randomized Controlled Trial of a Health Communication Intervention for Latinas.

照顾好自己和患乳腺癌的风险 (CUIDARSE)：拉丁裔健康传播干预措施的随机对照试验。

• 发表时间: 2020
• 作者: Payán, Denise D;Maggard;Flórez, Karen R;Mejía, Nelly;Hemmelgarn, Marian;Kanouse, David;Kahn, Katherine L;Golinelli, Daniela;Diaz Fuentes, Claudia M;Newberry, Sydne J;Lara, Marielena
• 通讯作者: Lara, Marielena