CTSA INFRASTRUCTURE FOR CLINICAL TRIALS

CTSA 临床试验基础设施

• 批准号: 8173807
• 负责人: Julian Solway
• 金额: $ 167.58万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173807
• 关键词: Clinical Trials; Research Infrastructure

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The ultimate goals of the University of Chicago CTSA program are to train scientists and health care providers at the University, our partner institutions, and our Community to determine the molecular underpinnings of disease or disease predisposition in any individual patient; to develop, test, implement, and make readily available to residents in our Community personalized therapies directed toward those individual underpinnings; and to do this in a way that is rigorous, valid, efficient, ethical, and respectful of our Community's needs and values. In a robust alliance with Argonne National Laboratory, the Illinois Institute of Technology, and two large healthcare organizations, we will undertake three bold new steps that will transform clinical and translational research at our institutions and in our Community: 1) Creation of an Institute for Translational Medicine, a new University-wide structure to collect, integrate, and disseminate the intellectual, organizational, and resource infrastructure needed to promote and support multidisciplinary translational research collaborations; 2) Synergistic research interaction with a new UC Urban Health Initiative which, through partnership with Community stakeholders, aims to improve Community health care access and quality, to build health literacy and trust throughout the Community, to enhance a translational research program informed by and responsive to the needs of the Community, and so to reduce health disparities; and 3) Establishment of a new academic Committee on Clinical and Translational Science and of multiple novel training programs to encourage and develop careers in clinical and translational research, intended for high school students through university faculty and across the entire translational research spectrum. Our consortium of dedicated CTSA investigators will employ a systems medicine approach to leverage their particular expertise in social science, genetic medicine, and integrative therapeutics. Together, this team and these transforming innovations will allow the University of Chicago CTSA to prepare the next generation of clinical and translational researchers to realize our vision of widely available, effective, and personalized therapies that find everyday application in Community practice and thereby reduce health disparities in diverse adult populations.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 芝加哥大学 CTSA 计划的最终目标是培训大学、我们的合作机构和社区的科学家和医疗保健提供者，以确定任何个体患者疾病或疾病易感性的分子基础；开发、测试、实施并向我们社区的居民提供针对这些个人基础的个性化治疗；并以严格、有效、高效、道德和尊重我们社区的需求和价值观的方式做到这一点。在与阿贡国家实验室、伊利诺伊理工学院和两家大型医疗保健组织的强有力联盟中，我们将采取三个大胆的新步骤，这将改变我们机构和社区的临床和转化研究： 1) 创建一个研究所转化医学，一个新的大学范围内的结构，用于收集、整合和传播促进和支持多学科转化研究合作所需的知识、组织和资源基础设施； 2) 与新的加州大学城市健康倡议进行协同研究互动，该倡议通过与社区利益相关者合作，旨在改善社区医疗保健的可及性和质量，在整个社区内建立健康素养和信任，加强以信息为基础并做出响应的转化研究计划满足社区的需求，从而减少健康差距； 3) 建立一个新的临床和转化科学学术委员会，并制定多个新颖的培训计划，以鼓励和发展临床和转化研究职业，面向高中生、大学教师和整个转化研究领域。我们的 CTSA 专门研究人员联盟将采用系统医学方法来利用他们在社会科学、遗传医学和综合治疗方面的特殊专业知识。这个团队和这些变革性创新将使芝加哥大学 CTSA 培养下一代临床和转化研究人员，以实现我们的愿景，即广泛可用、有效和个性化的疗法，这些疗法可以在社区实践中日常应用，从而减少健康差异在不同的成年人群中。