CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8173871
• 负责人: S. CLAIBORNE JOHNSTON
• 金额: $ 197.55万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173871
• 关键词: Research; Research Infrastructure

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. Despite explosive gains in our understanding of the basic mechanisms of human disease, meaningful translation of this knowledge to the treatment and prevention of disease has moved slowly. To accelerate the pace at which- discoveries in basic science can serve the health of our patients and community, we intend to establish a Clinical and Translational Science Institute (CTSI) at the University of California, San Francisco (UCSF).' Its mission will be to create a comprehensive, integrated academic home that promotes research and education in clinical and translational science at UCSF, at affiliated institutions, and in participating communities. Its goals are: (1) to support, enhance, and integrate existing training programs, increasing the number of trainees from diverse disciplines and improving the quality of their training in clinical and translational research methods; (2) to support, improve, and integrate existing infrastructure to enhance the design and implementation of clinical and translational studies, fostering collaborations to achieve a diverse spectrum of high quality, original research; (3) to enhance career development of clinical and translational researchers by providing mentoring and opportunities to catalyze original research and by changing the academic culture to appropriately reward multidisciplinary collaborative work; (4) to create a "Virtual Home" providing contemporary communications to simplify collaboration, to provide an optimal informatics matrix for conducting innovative research, and to nurture the growth of clinical and translational science. To reach these- goals, UCSF is transforming its clinical and translational research organization to establish 13 interrelated programs that will provide the training, services, and opportunities needed. These programs are led by senior scientists drawn from diverse disciplines:in each of UCSF's four health science schoolsDentistry, Medicine, Nursing, and Pharmacyand its Graduate Division. The plans reflect input from more than 200 interested, energetic, and committed participants from .throughout the community, including most of UCSF's academic leaders. These individuals worked collaboratively to ensure inclusion, transparency, and flexibility in the design and planned implementation of the CTSI. A significant financial commitment to the CTSI vision has been provided by the four schools ($13,368,750) and by the Chancellor's Office ($19,186,613). We believe that this infusion of new energy and resources will create and sustain a rich environment for innovative research and drive the realization of UCSF's full potential to educate and to support the work of clinical and translational scientists. If so, biomedicine will be advanced and the health of our patients and the community will benefit.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 尽管我们对人类疾病基本机制的理解取得了爆炸性进展，但将这些知识有意义地转化为疾病的治疗和预防的进展却进展缓慢。为了加快基础科学发现为患者和社区健康服务的步伐，我们打算在加州大学旧金山分校 (UCSF) 建立临床和转化科学研究所 (CTSI)。其使命是创建一个全面、综合的 促进加州大学旧金山分校、附属机构和参与社区的临床和转化科学研究和教育的学术之家。其目标是：（1）支持、加强和整合现有的培训项目，增加来自不同学科的学员数量，提高临床和转化研究方法的培训质量； (2) 支持， 改善和整合现有基础设施，以加强临床和转化研究的设计和实施，促进合作以实现各种高质量的原创研究； (3) 通过提供指导和促进原创性研究的机会以及改变学术文化以促进临床和转化研究人员的职业发展 适当奖励多学科协作工作； (4) 创建一个“虚拟家园”，提供现代通信以简化协作，为开展创新研究提供最佳信息学矩阵，并培育临床和转化科学的发展。 为了实现这些目标，加州大学旧金山分校正在将其临床和转化研究组织转变为 制定 13 个相互关联的计划，提供所需的培训、服务和机会。 这些项目由来自不同学科的资深科学家领导：加州大学旧金山分校的四个健康科学学院牙科、医学、护理和药学及其研究生部。这 该计划反映了来自整个社区 200 多名感兴趣、充满活力和忠诚的参与者的意见，其中包括 UCSF 的大多数学术领导者。这些人通力合作，确保 CTSI 设计和计划实施的包容性、透明度和灵活性。四所学校（13,368,750 美元）和校长办公室（19,186,613 美元）为 CTSI 愿景提供了重大财政承诺。我们相信，这 新能源和资源的注入将为创新研究创造和维持一个丰富的环境，并推动加州大学旧金山分校充分发挥教育和支持临床和转化科学家工作的潜力。如果是这样，生物医学将得到进步，我们的患者和社区的健康将受益。