Administrative Core

行政核心

• 批准号: 8306259
• 负责人: JOSEPH H. SZURSZEWSKI
• 金额: $ 52.64万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8306259
• 关键词: Administrative Coordination; Advisory Committees; Animal Model; Anorexia; Anorexia Nervosa; Basic Science; Budgets; Bulimia; Clinic; Clinical Research; Collaborations; Communication; Diabetes Mellitus; Disease; Eating Disorders; Ensure; Enteral; Future; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal tract structure; Image; Individual; Leadership; Mails; Patients; Physiological; Preparation; Principal Investigator; Program Reviews; Research; Research Personnel; Resources; Science; Stomach; Structure; System; Telephone; Translational Research; bioimaging; cell motility; data management; experience; meetings; motility disorder; mouse model; programs

The renewal of this Program Project "Pathobiology of the Enteric System" builds upon the significant advances and accomplishments achieved during the first four years of this Program Project as well as on the extensive experience and superb record of accomplishments in the basic, clinical and translational research in gastrointestinal motility at the Mayo Clinic. This Program Project focuses on dysregulation of motility of the gastrointestinal tract in patients with diabetes and in animal models of diabetes and in mouse models of anorexia nervosa and bulimia nervosa. It expands our existing research portfolio to include research on gastric dysmotilities in these eating disorders because dysmotilities of the stomach and gastric emptying disorders seen in anorexia and bulimia nervosa mirror those seen in diabetes. This renewal request includes new staff investigators in neurogastroenterology and biomedical imaging sciences. Thus, considerable coordination and administrative effort is essential to manage this program. The Administrative Core A: (1) ensures that adequate progress is made on all projects; (2) supervises and coordinates the preparation of budgets; (3) reviews and evaluates Imaging Core B and Physiological Characterization and Data Management Core C and their resource utilization; (4) develops plans for future initiatives; (5) manages all issues and communications within relevant administrative entities at Mayo Clinic and extramurally; (6) coordinates the meetings of the Executive Committee of Administrative Core A and the Internal Advisory Committee; and (7) coordinates the annual meeting of the External Advisory Committee. Implementation and management of the Program Project will be facilitated through the leadership of the Principal Investigator, Dr. Joseph H. Szurszewski, through the Executive Committee by formal bimonthly meetings, and as needed, by telephone calls and e-mails. Assessment of scientific progress and facilitation of collaboration between the projects and cores will be accomplished through the bimonthly meetings with the Executive Committee and with the Project Leaders of the individual projects and with Directors of Imaging Core B and Physiological Characterization and Data Management Core C, review of the meetings with the Internal Advisory Committee and by annual formal review of the Program by the External Advisory Committee.

该计划项目“肠系统病理生物学”的续签是基于该计划项目的前四年所取得的重大进步和成就，以及在Mayo Clinic在胃肠道运动基本，临床和转化研究中成就的丰富经验和超级记录。该计划项目的重点是糖尿病患者以及糖尿病动物模型以及神经性厌食症和神经性贪食症的小鼠模型中胃肠道运动的失调。它扩大了我们现有的研究组合，包括对这些饮食失调的胃不良障碍的研究，因为胃和胃排空疾病的失调性在厌食症和神经性神经性贪食症中都反映了糖尿病中看到的疾病。该更新请求包括神经胃病学和生物医学成像科学的新员工调查员。因此，大量的协调和行政努力对于管理该计划至关重要。行政核心A：（1）确保在所有项目上都取得了足够的进展； （2）监督和协调预算的准备； （3）审查和评估成像核心B和生理表征以及数据管理核心C及其资源利用； （4）制定未来计划的计划； （5）管理Mayo诊所和外部彩色的相关行政实体内的所有问题和通讯； （6）协调行政核心A执行委员会和内部咨询委员会的会议； （7）协调外部咨询委员会的年度会议。该计划项目的实施和管理将通过首席调查员Joseph H. Szurszewski博士的领导来促进，并通过正式的双月召开会议，并根据需要通过电话和电子邮件来促进。评估项目和核心之间的科学进步和协作促进，将通过与执行委员会以及各个项目的项目负责人以及成像核心B和生理学特征和数据管理核心C的董事，与内部咨询委员会的会议以及外部咨询委员会的年度正式审查有关。