South Texas Pediatric Minority Based CCOP

南德克萨斯州儿科少数民族 CCOP

• 批准号: 8323685
• 负责人: ANNE-MARIE R. LANGEVIN
• 金额: $ 5万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-09-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8323685
• 关键词: Address; Admixture; Adolescent; Affect; Area; Cancer Patient; Cardiovascular Diseases; Child; Childhood; Clinical; Clinical Trials; Community Clinical Oncology Program; Development; Diabetes Mellitus; Funding; Genes; Genetic; Genetic Polymorphism; Health; Health Sciences; Incidence; Institution; Malignant Childhood Neoplasm; Malignant Neoplasms; Medical center; Methodist Church; Mexican Americans; Minority; Minority-Based Community Clinical Oncology Program; Morbidity - disease rate; Obesity; Orphan; Outcome; Patients; Pediatric Hematology/Oncology; Pediatric Hospitals; Pediatric Oncology; Physicians; Pilot Projects; Population; Principal Investigator; Rosa; Services; South Texas; Survivors; Texas; United States; Universities; Wing; Youth; base; cancer care; cancer risk; care delivery; chemotherapy; liver function; liver metabolism; mortality; oncology program; population based; socioeconomics; standard of care; young adult

The South Texas Pediatric Minority-Based Community Clinical Oncology Program (STP-MB-CCOP) was first formed in 1990, is currently in its 17th year of funding and is one of two solely pediatric CCOPs in the United States. The Principal Investigator of the STP-MB-CCOP has traditionally been a physician in the Division of Pediatric Hematology/Oncology of the University of Texas Health Science Center at San Antonio (UTHSCSA). The STP-MB-CCOP operates as a consortium of 4 pediatric institutions: 1) CHRISTUS Santa Rosa Children's Hospital (CSRCH) (San Antonio, TX); 2) Driscoll Children's Hospital (Corpus Christi, TX); 3) Methodist Children's Hospital (San Antonio, TX), and 4) the U.S. Army pediatric oncology program at Wilford Hall Medical Center (San Antonio, TX). The STP-MB-CCOP will continue to provide access to the highest standard of care (i.e. access to clinical trials) to the youth population of South Texas affected by cancer. In addition, it will continue to expand its wings in regards to population-based studies dealing with health and socio-economic issues specific to the population of South Texas. ¿ It will target the orphans of cancer care delivery (i.e. adolescents and young adults with cancer) in order to understand and abolish the barriers interfering with their access to clinical trials and survival. ¿ It will concentrate on bringing access to clinical trials to pediatric cancer patients residing in the Lower Rio Grande Valley. ¿ It will further assess the impact of obesity on the survival of ALL patients by addressing issues such as: 1) genetics of obesity; 2) possible impact of obesity on the development of ALL; 3) impact of obesity on liver function and metabolism of chemotherapy agents used to treat ALL; and 4) impact of obesity on later development of diabetes and cardiovascular disease in ALL survivors. ¿ It will serve as a clinical base for genetic studies characterizing the pediatric cancer population in border population including genetic admixture and polymorphism studies in genes influencing both cancer risks and outcomes. ¿ It will be used to develop additional pilot studies that will address the uniqueness (biologic or socio-economic) of the youth population of South Texas affected by cancer.

南德克萨斯州小儿少数民族的社区临床肿瘤学计划（STP-MB-CCOP）于1990年首次成立 目前正处于17年的资金中，是美国两个唯一的儿科CCOP之一。主要研究员 传统上，STP-MB-CCOP是德克萨斯大学儿科血液学/肿瘤学系的物理学 圣安东尼奥（UTHSCSA）的健康科学中心。 STP-MB-CCOP作为4个儿科机构的财团运营：1） 克里斯托斯·圣罗莎儿童医院（CSRCH）（德克萨斯州圣安东尼奥）； 2）Driscoll儿童医院（德克萨斯州科珀斯克里斯蒂）； 3） 卫理公会儿童医院（德克萨斯州圣安东尼奥）和4）美国陆军儿科肿瘤学计划 （德克萨斯州圣安东尼奥）。 STP-MB-CCOP将继续为青年提供最高标准的护理（即获得临床试验） 南德克萨斯州受癌症影响的人口。此外，它将继续扩大基于人群的翅膀 涉及针对南德克萨斯州人口的健康和社会经济问题的研究。 它将针对癌症护理分娩的孤儿（即青少年和癌症年轻人），以了解和废除障碍，以干扰他们获得临床试验和生存。 »它将集中于为居住在下里奥格兰德山谷的小儿癌症患者带来临床试验。 �将通过解决以下问题来进一步评估肥胖对所有患者生存的影响：1）肥胖的遗传学； 2） 肥胖对所有人发展的可能影响； 3）肥胖对化疗的肝功能和代谢的影响 用来治疗所有人的代理商； 4）肥胖对所有生存中糖尿病和心血管疾病的后来发展的影响。 »它将作为表征边境人口小儿癌人群的遗传研究的临床基础 在影响癌症风险和结果的基因中的遗传混合和多态性研究。 »它将用于开发其他试点研究，以解决青年的独特性（生物或社会经济） 南德克萨斯州受癌症影响的人口。