Children with Epilepsy in Developing Countries

发展中国家的癫痫儿童

• 批准号: 8403445
• 负责人: HARRY CHUGANI
• 金额: $ 1万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8403445
• 关键词: Address; Africa; Africa South of the Sahara; African; Area; Caring; Child; Child Care; Childhood; Clinical; Collaborations; Congresses; Country; Critiques; Data; Developing Countries; Diagnosis; Drug Formulations; Educational Activities; Educational workshop; Epilepsy; Evaluation; Expert Opinion; Fostering; Funding; Goals; Guidelines; Health system; Human Resources; Individual; International; Knowledge; Life; Location; Mission; Neurologic; Neurologist; Pediatric Neurology; Pharmaceutical Preparations; Prevalence; Principal Investigator; Public Health; Publications; Research; Research Training; Resources; Series; Services; Societies; Specialist; Study Section; Training; Training and Education; Treatment Cost; Update; World Health Organization; Writing; base; meetings; pediatrician; programs; response

DESCRIPTION (provided by applicant): The World Health Organization estimates that 80% of the 50 million people in the world with epilepsy live in developing countries (WHO, 2004). The true prevalence of children with epilepsy in Africa is not known, but figures range from 2.9-26 per 1000 children. More importantly, the treatment gap (defined as the proportion of cases with active convulsive epilepsy without drug treatment) is an astonishing 70.3%. The attributed causes for the treatment gap are related to inadequacies of the health systems, mainly inadequate skilled manpower, cost of treatment and unavailability of drugs for epilepsy. While most countries have access to general pediatricians, few have pediatric neurology services and only 4 out of 15 African countries have an established pediatric neurology association or society. In response to these inadequacies, the present proposal seeks funding to hold a 3-day research program on the clinical aspects of childhood epilepsy in Africa in an effort to collect th necessary data aimed at determining how to elevate the standard of epilepsy diagnosis and treatment in sub-Saharan African countries. We seek to invite a colloquium of specialists from Africa and abroad to discuss optimal epilepsy care for children in sub-Saharan Africa. Research questions that will be addressed are: (i) the status quo of childhood epilepsy in sub-Saharan Africa, (i) guidelines for the optimal management of children with epilepsy through current practice parameters from organizations such as World Health Organization (WHO) and International League Against Epilepsy (ILAE) and whether and to what extent these guidelines are viable to be applied in sub-Saharan Africa, (iii) causes for the knowledge gap in relation to children with epilepsy in sub-Saharan Africa, and (iv) defining the best strategies to reduce the treatment gap in children with epilepsy in sub- Saharan Africa. The research data collected from this workshop and subsequent implementation of changes will be presented in a series of publications.

描述（由申请人提供）：世界卫生组织估计，世界上 5000 万癫痫患者中的 80% 生活在发展中国家（WHO，2004）。非洲儿童癫痫的真实患病率尚不清楚，但数字范围为每 1000 名儿童 2.9-26 名。更重要的是，治疗差距（定义为未经药物治疗的活动性惊厥性癫痫病例比例）达到惊人的70.3%。造成治疗差距的原因与卫生系统的不足有关，主要是技术人员不足、治疗费用和癫痫药物的缺乏。虽然大多数国家都有普通儿科医生，但很少有国家提供儿科神经病学服务，而且 15 个非洲国家中只有 4 个国家建立了儿科神经病学协会或协会。 针对这些不足，本提案寻求资助在非洲开展为期 3 天的儿童癫痫临床研究项目，以收集必要的数据，以确定如何提高非洲癫痫诊断和治疗的水平。撒哈拉以南非洲国家。 我们寻求邀请来自非洲和国外的专家召开座谈会，讨论撒哈拉以南非洲儿童的最佳癫痫护理。将解决的研究问题包括：(i) 撒哈拉以南非洲地区儿童癫痫的现状，(i) 通过世界卫生组织 (WHO) 和国际抗癫痫联盟 (ILAE) 以及这些指南是否以及在多大程度上适用于撒哈拉以南非洲地区，(iii) 撒哈拉以南非洲地区癫痫儿童相关知识差距的原因，以及 (iv)定义缩小撒哈拉以南非洲地区癫痫儿童治疗差距的最佳策略。从本次研讨会收集的研究数据以及随后实施的变革将在一系列出版物中呈现。

项目成果

Children with epilepsy in Africa: recommendations from the International Child Neurology Association/African Child Neurology Association Workshop.

非洲癫痫儿童：国际儿童神经病学协会/非洲儿童神经病学协会研讨会的建议。

• DOI: 10.1177/0883073813482974
• 发表时间: 2013
• 期刊: Journal of child neurology
• 影响因子: 1.9
• 作者: Wilmshurst,JoM;Cross,JHelen;Newton,Charles;Kakooza,AngelinaM;Wammanda,RobinsonD;Mallewa,Macpherson;Samia,Pauline;Venter,Andre;Hirtz,Deborah;Chugani,Harry
• 通讯作者: Chugani,Harry