Analytical Lab

分析实验室

• 批准号: 7491884
• 负责人: JILL MARIE KOLESAR
• 金额: $ 16.52万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-23 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7491884
• 关键词: Arts; Biochemical; Biological Assay; Cancer Center; Clinical; Clinical Chemoprevention; Clinical Trials; Data Analyses; Development; Drug Kinetics; Equipment; Genotype; Housing; Laboratories; Maintenance; Methodology; Methods; Mission; Monitor; Mutation; New Agents; Performance; Pharmacodynamics; Pharmacogenetics; Phase; Process; Research Personnel; Sampling; Services; Shipping; Ships; anticancer research; design; foot; instrument; instrumentation; member; progesterone 11-hemisuccinate-(2-iodohistamine)

The mission of the Analytical Laboratory for Pharmacogenetics, Pharmacodynamics and Pharmacokinetics (3P) is to advance clinical cancer research by providing accurate and efficient state of the art data and analyses of pharmacogenetics, pharmacodynamics and pharmacokinetics parameters. The 3P Laboratory has three services available to Cancer Center members, instrumentation, analytical service and the sample acquisition service. 1. Instrumentation The 3P Laboratory maintains and instructs Cancer Center members on the use of all laboratory equipment housed in the 3P Laboratory. The 3P Laboratory has 1,200 square feet of laboratory space and 240 square feet of office space which house over 25 laboratory instruments. The space was specially designed for efficient use and maintenance of analytical instruments. The laboratory design also facilitates timely and efficient processing of clinical samples. 2. Analytical Services The 3P Laboratory is designed as a facility for developing and executing a wide variety of bioanalytical methods, including processing and analyzing samples for PK/PD/PG studies in support of Phase I, II, III and chemoprevention clinical trials. This service includes development and performance of original assays for new agents, assays to monitor endogenous biochemicals, genotyping and mutation assays and adaptation of existing methodology for analyses where applicable. 3. Sample Acquisition Services (SAS) The 3P Laboratory also offers a Sample Acquisition Service for all UWCCC clinical trials. This service is offered to all investigators participating in clinical trials requiring acquisition, processing, storage and shipping of samples for PK/PD/PG studies.

药物遗传学、药效学和药代动力学分析实验室的使命 (3P) 是通过提供准确、高效的最新数据和技术来推进临床癌症研究 药物遗传学、药效学和药代动力学参数分析。 3P 实验室为癌症中心成员提供三项服务：仪器、分析 服务和样品获取服务。 1. 仪器仪表 3P 实验室维护并指导癌症中心成员使用所有实验室设备 位于 3P 实验室。 3P实验室拥有1,200平方英尺的实验室空间和240平方英尺的空间 英尺的办公空间，容纳超过 25 台实验室仪器。该空间是专门为 有效使用和维护分析仪器。实验室设计还有助于及时和 有效处理临床样本。 2. 分析服务 3P 实验室被设计为开发和执行各种生物分析的设施 方法，包括处理和分析用于 PK/PD/PG 研究的样品，以支持 I、II、III 期和 化学预防临床试验。该服务包括原始检测的开发和执行 新药剂、监测内源生化物质的测定、基因分型和突变测定以及适应 适用时的现有分析方法。 3. 样品采集服务（SAS） 3P 实验室还为所有 UWCCC 临床试验提供样品采集服务。这项服务是 提供给参与需要采集、处理、储存和运输的临床试验的所有研究人员 用于 PK/PD/PG 研究的样本。