THYROID ACTION IN THE HEART

甲状腺在心脏中的作用

• 批准号: 7722446
• 负责人: Wolfgang H Dillmann
• 金额: $ 0.98万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7722446
• 关键词: Cardiac Myocytes; Computer Retrieval of Information on Scientific Projects Database; Endothelial Cells; Funding; Grant; Heart; Institution; Protein Isoforms; Research; Research Personnel; Resources; Role; Source; Thyroid Gland; Thyroid Hormone Receptor; United States National Institutes of Health; cell type; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project is designed to clarify the mechanisms which underlie Thyroid hormone receptor (T3R) isoform specific effects in the heart. We will investigate the functional role of T3R in the cardiac myocytes and heart microvascular endothelial cells. In addition, the distribution of the different isoform of T3Rs will be determined in the different cell types.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 该项目旨在阐明甲状腺激素受体（T3R）亚型对心脏产生特异性作用的机制。我们将研究 T3R 在心肌细胞和心脏微血管内皮细胞中的功能作用。此外，T3R 不同亚型的分布将在不同细胞类型中确定。