Intracellular Calcium Release Channels and Cardiac Arrhythmias

细胞内钙释放通道与心律失常

• 批准号: 8236895
• 负责人: ANDREW Robert MARKS
• 金额: $ 31.92万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8236895
• 关键词: Accounting; Address; Affinity; Animals; Anti-Arrhythmia Agents; Arrhythmia; Binding; Binding Proteins; Calcium; Calcium Channel; Calcium Signaling; Canis familiaris; Cardiac; Cardiac Myocytes; Cell physiology; Collaborations; Complementary DNA; Complex; Coupling; Cyclic AMP-Dependent Protein Kinases; Data; Defect; Development; Engineering; Equilibrium; Event; Evolution; Exercise; Exhibits; FK506; FKBP1B gene; Funding; Gated Ion Channel; Genes; Genetic; Goals; Heart; Heart failure; Homeostasis; Human; Immunosuppressive Agents; Ion Channel; Knock-in Mouse; Laboratories; Lead; Link; Macromolecular Complexes; Milrinone; Mind; Modeling; Molecular; Molecular Probes; Molecular Target; Mus; Mutant Strains Mice; Mutation; Names; Oryctolagus cuniculus; PDE4D3; PDE4D3 phosphodiesterase; Patients; Pharmaceutical Preparations; Phosphoric Monoester Hydrolases; Phosphorylation; Physiological; Play; Predisposition; Process; Proteins; Recombinants; Regulation; Relative (related person); Role; Rolipram; RyR1; RyR2; Ryanodine Receptor Calcium Release Channel; SERCA2a; Signal Transduction; Site; Stress; Sudden Death; Surface; Tacrolimus Binding Protein 1A; Tacrolimus Binding Proteins; Testing; Therapeutic; Toxic effect; Variant; Ventricular Arrhythmia; Ventricular Tachycardia; Work; base; cell growth regulation; cytosolic receptor; design; human disease; inhibitor/antagonist; man; mouse model; mutant; new therapeutic target; novel; phospholamban; phosphoric diester hydrolase; prevent; programs; protein function; research study; spinophilin; sudden cardiac death; uptake; voltage