The process of long term abstinence from opioid use among HIV+ respondents

HIV 受访者长期戒除阿片类药物的过程

基本信息

批准号：
8279209
负责人：
Nelson Jose Tiburcio
金额：
$ 15.03万
依托单位：
NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC.
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-06-15 至 2014-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8279209
关键词：
AIDS/HIV problem Abscess Abstinence Acquaintances Acquired Immunodeficiency Syndrome Affect African American Alcohol or Other Drugs use Anxiety Area Atlases Attitude Award Behavior Caring Centers for Disease Control and Prevention (U.S.)Cessation of life Child Cities Client Code Codeine Communicable Diseases Computer software Conflict (Psychology)Criminal Justice Data Data Analyses Disease susceptibility Documentation Dose Drug abuse Drug usage Drug user Emotional Face Family Family member Female Floods Focus Groups Friends Future Gender Group Interviews HIV HIV Seropositivity Health Health Personnel Heroin Heroin Users Household Individual Institution Intervention Interview Latino Legal Life Life Experience Maintenance Marketing Measures Medication Management Meditation Mental Depression Mental Health Methods Morphine Neighborhoods New York Opioid Overdose Oxycodone Participant Patient Self-Report Pattern Percocet Personal Satisfaction Persons Pharmaceutical Preparations Pharmacologic Substance Pilot Projects Policies Population Prayers Predisposition Prevalence Process Provider Public Health Public Speaking Recording of previous events Recovery Recruitment Activity Relapse Reporting Research Research Personnel Research Subjects Respondent Route Scheme Science Services Social Network Social Work Social support Spirituality Stigmatization Street Drugs Substance abuse problem Techniques Technology Test Result Treatment Protocols Vicodin Woman Work base career coping design disorder prevention experience insight loved ones male metropolitan offender opioid abuse opioid misuse physical conditioning pill prescription opioid research study response skin lesion social sound success tool transmission process

项目摘要

DESCRIPTION (provided by applicant): This qualitative study focuses on the strategies 70 HIV+ former opioid users employ to maintain wellness. HIV+ former opioid users who must simultaneously deal with HIV seropositivity, including medication management and institutional affiliation, amid an already difficult process of opioid recovery, pose multiple challenges not only for the individuals but also for their families/social networks. This re- submission application is being submitted under PAR-10-021 AIDS Science Track Award for Research Transition (A-START) by an Early Career Investigator. He has a long history of successfully engaging participants in street drug user studies, and will now focus on interviewing this population of HIV+ sustained abstainers who have ceased their opioid misuse for five or more years. The use of non- prescribed and/or abuse of opioids, particularly heroin, (but including a number of pharmaceutical pill forms - Oxycontin, Vicodin, Percocet, morphine, and even more recent syrup forms, i.e. "Lean") are associated with high relapse rates, infectious disease susceptibility, criminal justice involvement, and social disharmony. Qualitative researchers have developed technologies for recruiting and investigating the drug-using careers of active users, but have not often documented patterns of non-use. The data gathered from this exploratory pilot study of HIV seropositive former opioid users who have been able to maintain abstinence will serve as a platform for larger studies examining the intersection of HIV/AIDS, drug abuse, and public health issues. The former users in this study will be from the New York metropolitan area, all with histories of daily heroin and/or other illicit opioid use exceeding one year, greater than five years sustained abstinence from these substances, and HIV seropositive status as measured by self report. The project team will verify HIV status by asking for documentation (for example test results, correspondence from doctors, prescriptions for HIV medication, etc.). The open ended interview is designed to elicit information describing the process of their recovery as well as ascertain the co-occurrence of other physical and emotional issues. The Centers for Disease Control and Prevention suggests substance use, largely opioid use, is increasing as a primary HIV transmission route. This study holds promise for informing future interventions and sketching a roadmap to maintenance of recovery and wellness as demonstrated by HIV+ people with lived experience/s of abstinence from substance use.

描述（由申请人提供）：这项定性研究重点关注 70 名 HIV+ 前阿片类药物使用者用来维持健康的策略。 HIV+前阿片类药物使用者必须同时处理艾滋病毒血清阳性问题，包括药物管理和机构隶属关系，在阿片类药物恢复过程已经很困难的情况下，这不仅给个人而且给他们的家庭/社交网络带来了多重挑战。此重新提交申请是由一位早期职业研究者根据 PAR-10-021 艾滋病科学轨道研究转型奖 (A-START) 提交的。他在成功让参与者参与街头吸毒者研究方面拥有悠久的历史，现在将重点采访这些已停止滥用阿片类药物五年或更长时间的艾滋病毒+持续戒毒者。使用非处方和/或滥用阿片类药物，特别是海洛因（但包括许多药丸形式 - 奥施康定、维柯丁、Percocet、吗啡，以及甚至更新的糖浆形式，即“Lean”）与高浓度相关。复发率、传染病易感性、刑事司法参与和社会不和谐。定性研究人员已经开发出用于招募和调查活跃使用者的吸毒生涯的技术，但通常没有记录不吸毒的模式。这项针对艾滋病毒血清反应呈阳性的前阿片类药物使用者（能够保持戒断）的探索性试点研究收集的数据将作为更大规模研究的平台，以审查艾滋病毒/艾滋病、药物滥用和公共卫生问题的交叉点。这项研究中的前使用者将来自纽约大都市区，他们都有超过一年的每日海洛因和/或其他非法阿片类药物使用史，持续戒除这些物质超过五年，并且通过自我测量患有艾滋病毒血清阳性状态报告。项目团队将通过索取文件（例如检测结果、医生信函、艾滋病毒药物处方等）来验证艾滋病毒状况。开放式访谈旨在获取描述他们康复过程的信息，并确定其他身体和情感问题的同时发生。疾病控制和预防中心表明，物质使用（主要是阿片类药物的使用）正在增加，成为艾滋病毒的主要传播途径。这项研究有望为未来的干预措施提供信息，并勾画出维持康复和健康的路线图，正如具有戒毒经历的艾滋病病毒感染者所证明的那样。