Quit IT: Development of a Web-based 3D Coping Skills Game to Increase Self-Effic

退出 IT：开发基于 Web 的 3D 应对技巧游戏以提高自我效能

• 批准号: 8237475
• 负责人: Jamie S. Ostroff
• 金额: $ 42.52万
• 依托单位: MUZZY LANE SOFTWARE, INC.
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8237475
• 关键词: Abstinence; Accounting; Acute; Address; Admission activity; American; Area; Basic Science; Behavioral; Behavioral Sciences; Businesses; Cancer Patient; Cardiovascular system; Cessation of life; Clinical Research; Clinical Trials; Clinical Trials Design; Computer software; Computers; Coping Skills; Counseling; Cues; Data; Data Collection; Development; Diagnosis; Disease; Distress; Elements; Environment; Feedback; Foundations; Health; Health Expenditures; Health Technology; Home environment; Hospitalization; Hospitals; Household; Institutional Review Boards; Internet; Intervention; Investments; Life; Malignant Neoplasms; Manuscripts; Measurement; Mechanics; Memorial Sloan-Kettering Cancer Center; Modification; Motivation; National Cancer Institute; Newly Diagnosed; Nicotine Withdrawal; Online Systems; Patients; Pattern; Pharmacotherapy; Phase; Population; Population Heterogeneity; Preparation; Prevention Research; Prevention approach; Preventive Intervention; Procedures; Process; Production; Productivity; Protocols documentation; Public Health; Quality-Adjusted Life Years; Questionnaires; Randomized; Recruitment Activity; Recurrence; Relapse; Reporting; Research Personnel; Resources; Rewards; Risk; Schedule; Second Primary Cancers; Second Primary Neoplasms; Self Efficacy; Simulate; Smoke; Smoker; Smoking; Structure; Suggestion; Techniques; Technology; Telephone; Test Result; Testing; Tobacco; Tobacco Dependence; Tobacco Use Cessation; Tobacco use; Training; Translating; Treatment Effectiveness; Ursidae Family; Work; Writing; animation; assault; cancer diagnosis; cancer recurrence; cancer therapy; catalyst; cigarette smoking; commercialization; coping; cost; design; disorder later incidence prevention; disorder risk; experience; follow-up; high risk; improved; innovation; meetings; non-smoker; novel; premature; prevent; programs; prototype; psychologic; public health relevance; randomized trial; rehearsal; respiratory; simulation; smoking cessation; smoking relapse; software development; tool; treatment as usual; usability; virtual; virtual reality; volunteer

DESCRIPTION (provided by applicant): Tobacco use remains the single most preventable cause of premature deaths and cancer.1 Building on more than a decade of clinical and research experience in treating tobacco-dependence, we propose to address this problem with a new academic-small computer game business partnership that will develop a novel e-health tobacco cessation and relapse prevention product. Smoking relapse following a quit attempt remains a significant public health concern with high costs in quality-adjusted life years. A growing body of evidence suggests that continued practice, or behavioral rehearsal, can help smokers effectively manage smoking cues, and also that cues to smoke can be triggered virtually via interaction with a computer.2 Thus, we propose to create a 3D game intervention that aims to help smokers rehearse effective strategies and improve self- efficacy for managing smoking triggers. Given our preliminary work with this concept, our combined expertise, and the commercialization potential of this concept, we are pursuing a Fast Track submission. In Phase I we plan to transform our coping skills simulation developed in the virtual world Second Life to an accessible, structured gaming environment with elements essential for a full-fledged interactive game designed to promote tobacco cessation. Using a systematic feedback protocol, we will refine the game's usability, relevance and utility using patient volunteers recruited from the Memorial Sloan-Kettering Tobacco Cessation Program and behavioral science researchers with expertise in treating tobacco dependence. In Phase II we will incorporate alpha testing data and complete development of the coping skills game, including the 3D environment and game avatars, game design and scripts for coping skills, feedback and rewards for patients, and data collection capabilities. Then, using a randomized trial design conducted at Memorial Sloan-Kettering Cancer Center, we will test the game's potential to increase coping self-efficacy and decrease relapse to smoking among hospitalized cancer patients. Although rates of cessation among patients newly diagnosed with tobacco-related cancers are typically high, many continue to smoke or resume smoking shortly after discharge from the smoke- free, hospital environment.3-5 Despite often reporting high motivation to quit and serious consequences of continued smoking, cancer patients are at high risk for smoking relapse following hospitalization and an ideal population with which to test the potential of our game. We will randomize 190 patients using a two-group design (Usual Care + Smoking Cues Coping Skills Game vs. Usual Care Only) and gather self-efficacy and tobacco use data at 1, 3, and 6 months following hospitalization. The proposed study has the potential for high impact if our novel coping skills game shows efficacy for enhancing the treatment of tobacco dependence. This concept is highly marketable to a broad target audience of hospitalized smokers and may offer numerous benefits as an adjunct to current cessation interventions. PUBLIC HEALTH RELEVANCE: Tobacco use remains the single most preventable cause of premature deaths and cancer. Building upon over a decade of clinical and research experience in treating tobacco-dependence, we propose to address this problem with a new academic-small computer game business partnership that will develop a novel e-health tobacco cessation and relapse prevention product. The proposed study has the potential for high impact if our novel coping skills game shows efficacy for enhancing the treatment of tobacco dependence. This concept is highly marketable to a broad target audience of hospitalized smokers and may offer numerous benefits as an adjunct to current cessation interventions.

描述（由申请人提供）：烟草的使用仍然是过早死亡和癌症的最可预防的原因。1在治疗烟草依赖性的十多年中，建立了十多年的临床和研究经验，我们建议通过新的学术小型计算机游戏业务伙伴关系来解决这个问题，以开发出一种新型的E-Health Tobacco Cessco Cessation和Relape Pervicention。退出尝试后的吸烟复发仍然是一个重大的公共卫生问题，因为质量调整后的终身年份成本很高。越来越多的证据表明，持续的练习或行为排练可以帮助吸烟者有效地管理吸烟线索，并且可以通过与计算机的互动实际上触发吸烟线索。2因此，我们建议我们创建3D游戏干预措施，旨在帮助吸烟者进行有效的策略并提高自我效率，以提高自我效率来管理吸烟的弹力。为吸烟型烟草制作。鉴于我们从这个概念，我们的综合专业知识以及该概念的商业化潜力的初步工作，我们正在追求快速提交。在第一阶段，我们计划将在虚拟世界第二生活中开发的应对技能模拟转变为一个可访问的结构化游戏环境，其元素对于旨在促进烟草停止的全面互动游戏必不可少。使用系统的反馈协议，我们将使用从纪念斯隆 - 凯特（Sloan-Kettering）戒烟计划中招募的患者志愿者来完善游戏的可用性，相关性和实用性，以及在治疗烟草依赖方面具有专业知识的行为科学研究人员。在第二阶段，我们将结合Alpha测试数据并完整开发应对技能游戏，包括3D环境和游戏化身，游戏设计和脚本，以应对患者的应对技能，反馈和奖励以及数据收集功能。然后，使用在纪念斯隆 - 凯特林癌症中心进行的随机试验设计，我们将测试游戏增加应对自我效能感并减少住院癌症患者吸烟的潜力。尽管新诊断为烟草相关癌症的患者的停止率通常很高，但许多人在免疫，医院环境中排出后不久会吸烟或恢复吸烟。3-5经常报告戒烟的动机高，持续吸烟的严重后果，但癌症患者对住院后的吸烟和理想的人群来测试我们的游戏。我们将使用两组设计（通常的护理 +吸烟提示应对技巧与通常的护理）随机对190名患者进行随机分配，并在住院后1、3和6个月收集自我效能感和烟草使用数据。如果我们的新颖的应对技巧游戏显示出增强烟草依赖治疗的功效，则拟议的研究可能会产生高影响。这个概念对住院吸烟者的广泛目标受众来说是高度销售的，并且可能会为当前戒烟干预提供许多好处。 公共卫生相关性：烟草使用仍然是过早死亡和癌症的最可预防的原因。在十多年的临床和研究经验的基础上，我们建议通过新的学术小型计算机游戏业务合作伙伴关系解决这个问题，该伙伴将开发一种新型的电子健康烟草戒烟和预防复发产品。如果我们的新颖的应对技巧游戏显示出增强烟草依赖治疗的功效，则拟议的研究可能会产生高影响。这个概念对住院吸烟者的广泛目标受众来说是高度销售的，并且可能会为当前戒烟干预提供许多好处。