Analysis of the Exon Junction Complex in Neural Development and Microcephaly

神经发育和小头畸形中外显子连接复合体的分析

• 批准号: 8181166
• 负责人: Debra Silver
• 金额: $ 24.9万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2013-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8181166
• 关键词: Academic Medical Centers; Accounting; Address; Affect; Binding; Biological; Brain; Brain Stem; Cell Maintenance; Cell division; Cell physiology; Cells; Centrosome; Cerebral cortex; Chromosomes; Clinical; Complex; Data; Defect; Development; Development Plans; Diagnostic; Disease; Embryology; Etiology; Exons; Foundations; Future; Genes; Genetic; Genome Stability; Goals; Grant; Hela Cells; Hereditary Disease; Instruction; Knowledge; Mental Retardation; Microcephaly; Mitosis; Mitotic spindle; Modeling; Mus; Mutant Strains Mice; Mutation; National Human Genome Research Institute; Neocortex; Neurodegenerative Disorders; Neurons; Nonsense-Mediated Decay; Organ; Phase; Phenotype; Population; Positioning Attribute; Process; Production; Proteins; RNA; RNA Binding; RNA Splicing; RNA-Binding Proteins; Rare Diseases; Regulation; Research Personnel; Research Proposals; Role; Stem cells; Syndrome; Testing; Therapeutic; Training; Translations; United States National Institutes of Health; Ventricular; base; brain size; career; career development; genetic pedigree; insight; mouse model; mutant; nerve stem cell; neurodevelopment; neurogenesis; neuron apoptosis; novel; stem cell division; stem cell population; success