Novel Subunit of NF-kB Confers Gene Regulatory Specificity

NF-kB 的新亚基赋予基因调控特异性

• 批准号: 8202679
• 负责人: Fengyi Wan
• 金额: $ 24.15万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-05 至 2013-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8202679
• 关键词: 20 year old; Address; Affinity; Affinity Chromatography; Apoptosis; Award; B-Lymphocytes; Binding; Binding Sites; Biochemical; Biochemical Pathway; Biological Assay; Cell Line; Cell Nucleus; Cell physiology; Cells; Chronic; Complex; Cytoplasm; DNA; DNA Binding; DNA Sequence; Data; Disease; Electrophoretic Mobility Shift Assay; Environment; Evolution; Faculty; Gene Expression; Gene Expression Profile; Gene Expression Regulation; Gene Targeting; Genes; Genetic Transcription; Goals; Heterogeneous-Nuclear Ribonucleoprotein K; Human; IL2RA gene; Immune response; Immunoglobulins; In Vitro; Inflammation; Inflammatory; Ink; Instruction; Interleukin-2; Intervention; KH Domain; Knowledge; Length; Ligands; Light; Link; Malignant Neoplasms; Mammalian Cell; Maps; Mass Spectrum Analysis; Mediating; Mentorship; Microarray Analysis; Modeling; Molecular; Mus; NF-kappa B; Nuclear Extract; Pathway interactions; Peptides; Peripheral Blood Lymphocyte; Phase; Physiological; Physiological Processes; Play; Positioning Attribute; Proteins; Public Health; Recombinants; Regulation; Regulator Genes; Reporter Genes; Research; Research Personnel; Role; Sequence Analysis; Signal Pathway; Signal Transduction; Site; Specificity; Superantigens; T-Cell Activation; T-Cell Lymphoma; T-Lymphocyte; TNFRSF5 gene; Tertiary Protein Structure; Therapeutic; Therapeutic Intervention; Time; Transcriptional Regulation; Universities; Viral Genes; Work; base; cancer therapy; career development; cell growth; cell type; chromatin immunoprecipitation; design; dimer; drug discovery; empowered; experience; improved; in vivo; in vivo Model; inhibitor/antagonist; innovation; insight; intercellular communication; model design; new therapeutic target; novel; p65; reconstitution; research study; response; ribosomal protein S3; skills; small molecule; synaptotagmin I; transcription factor