Biosocial Factors in Rehabilitation for Schizophrenia

精神分裂症康复中的生物社会因素

基本信息

批准号：
7425782
负责人：
JOHN Sinclair BREKKE
金额：
$ 51.41万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-01 至 2010-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7425782
关键词：
Acute Address Administrator Advocate Area Biosocial California Caring Clinical Clinical Research Clinical Services Collaborations Communities Community Practice Community Services Complement Data Collection Databases Diagnosis Effectiveness Elements Expenditure Fostering Funding Goals Heterogeneity Independent Living Individual Intervention Knowledge Laboratories Link Literature Los Angeles Measures Mental Health Mental Health Services Mental disorders Methods Minority Neurocognition Neurocognitive Deficit Numbers Outcome Phase Practice based research Process Provider Psychophysiology Recording of previous events Recovery Rehabilitation therapy Research Research Infrastructure Research Personnel Schizophrenia Services Site Social Work Testing Training Support Translating Treatment outcome Universities base experience functional disability functional outcomes implementation research improved innovation programs psychobiologic psychosocial psychosocial rehabilitation rehabilitation service remediation social cognition

项目摘要

DESCRIPTION (provided by applicant): Recent literature in mental health services has identified a serious gap between what is known about mental disorders and their treatment from university-based clinical research and what services are actually provided to consumers in typical community practice settings. This IP-RISP "Biosocial Factors in Rehabilitation for Schizophrenia" will build a partnership between university-based clinical services researchers and practitioners and consumers from a psychosocial rehabilitation service agency. The goal of this IP-RISP is to implement a research and practice agenda that will translate recent findings on psychobiological deficits in schizophrenia and their remediation into community based rehabilitation practice. We will address questions relevant to: (i) improving the effectiveness of community-based psychosocial rehabilitation interventions for functional disability in schizophrenia, and (ii) adapting and infusing new knowledge and new interventions into psychosocial rehabilitation practice settings in the community. This IP-RISP will address four practice-research aims and two infrastructure aims. The four practice-research aims are: 1) To introduce knowledge on functional outcomes and psychobiological factors to practitioners and consumers of psychosocial rehabilitation services at Portals; 2) To partner with agency clinicians and consumers in adapting and infusing (transporting) psychosocial intervention strategies for the remediation of psychobiological deficits into existing rehabilitation services; 3) To partner with agency clinicians and consumers in implementing controlled pilot research on whether targeted psychobiological service elements increase the effectiveness of psychosocial rehabilitation services in the community by improving consumer outcomes; 4). To facilitate the sustainability of the new service configurations by incorporating consumer, practitioner, and administrator perspectives. The two infrastructure aims are: 5). To develop a shared university/agency infrastructure consisting of a database and shared clinical-research personnel specifically: a). To increase the clinical utility of an existing database used to measure psychosocial outcomes in a community psychosocial rehabilitation setting, and b). To train and support clinical-research personnel who will participate in both clinical and research agendas at the community service setting. 6). To build a platform for ongoing psychobiological data collection consisting of an agency-based laboratory for assessing and measuring relevant psychobiological variables such as neurocognition, social cognition, and psychophysiological responsivity. The aims will be met during four activity phases consisting of: a) partnering among agency staff, consumers, and researchers; b) introducing and adapting new service elements into rehabilitation practice; c) implementing pilot research on the effectiveness of the new intervention elements; and d) assessing the implementation experience.

描述（由申请人提供）：最近的精神卫生服务文献发现，大学临床研究对精神障碍及其治疗的了解与典型社区实践环境中实际向消费者提供的服务之间存在严重差距。该 IP-RISP“精神分裂症康复中的生物社会因素”将在大学临床服务研究人员、心理社会康复服务机构的从业者和消费者之间建立伙伴关系。该 IP-RISP 的目标是实施一项研究和实践议程，将有关精神分裂症心理生物学缺陷及其补救措施的最新发现转化为基于社区的康复实践。我们将解决以下相关问题：（i）提高基于社区的心理社会康复干预措施对精神分裂症功能障碍的有效性，以及（ii）将新知识和新干预措施调整并注入社区的心理社会康复实践环境中。该 IP-RISP 将解决四个实践研究目标和两个基础设施目标。四个实践研究目标是： 1) 向门户网站心理社会康复服务的从业者和消费者介绍有关功能结果和心理生物学因素的知识； 2) 与机构临床医生和消费者合作，调整和注入（转移）心理社会干预策略，以修复现有的康复服务中的心理生物学缺陷； 3) 与机构临床医生和消费者合作实施对照试点研究，研究有针对性的心理生物学服务要素是否可以通过改善消费者的结果来提高社区心理社会康复服务的有效性； 4).通过整合消费者、从业者和管理员的观点，促进新服务配置的可持续性。两个基础设施目标是：5)。开发一个共享的大学/机构基础设施，具体包括数据库和共享的临床研究人员：a)。提高用于测量社区心理康复环境中心理社会结果的现有数据库的临床实用性，b)。培训和支持将参与社区服务机构的临床和研究议程的临床研究人员。 6).建立一个持续的心理生物学数据收集平台，包括一个基于机构的实验室，用于评估和测量相关的心理生物学变量，如神经认知、社会认知和心理生理反应性。这些目标将通过四个活动阶段来实现，包括： a) 机构工作人员、消费者和研究人员之间的合作； b) 在康复实践中引入和调整新的服务要素； c) 对新干预要素的有效性进行试点研究； d) 评估实施经验。