Biostatistics and Data Management

生物统计学和数据管理

• 批准号: 8380299
• 负责人: Kathryn L Lunetta
• 金额: $ 106.68万
• 依托单位: ROSWELL PARK CANCER INSTITUTE CORP
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8380299
• 关键词: African American; Area; Bioinformatics; Biometry; Breast Cancer Epidemiology; Computer software; Data; Data Analyses; Data Collection; Data Set; Data Storage and Retrieval; Databases; Development; Ensure; Epidemiologic Studies; Funding; Genetic; Genetic Databases; Genetic Research; Individual; Laboratories; Lead; Manuscripts; Methods; Molecular Genetics; Multicenter Studies; Pathologic; Phase; Postdoctoral Fellow; Preparation; Prevention; Procedures; Productivity; Questionnaires; Research; Research Design; Research Personnel; Sampling; Scheme; Secure; Services; Statistical Distributions; Study Subject; Techniques; Woman; data integrity; data management; design; distributed data; experience; high standard; improved; malignant breast neoplasm; postdoctoral investigator; programs; research study

The Biostatistics and Data management Core, Core D, will support all phases of data management and analyses in this P01 project. It will create and manage both old and new genetic, pathologic, and questionnaire data from the four participating studies. It will develop and maintain procedures for preparing and distributing datasets across studies using secure methods. It will collaborate with Cores B and C and Project Leaders in study design and sampling schemes for the various Projects. It will provide methodologic and analytic expertise to project investigators including study design, conduct of data analytic plans, bioinformatics analyses, and interpretation of statistical results. The Core will be responsible for data harmonization so that all investigators are using the same variable definitions. The Core will carry out many of the data analyses and has state-of-the-art hardware and software for doing so. The Core will collaborate closely with postdoctoral fellows and investigators on the individual Projects. The Leader of the Core and other Core investigators have expertise in genetics research and have had extensive experience in managing and analyzing the data of large multicenter studies. The activities of the Core will maintain high standards for data collection and analysis, maintain the integrity of the data, achieve consistency across the studies, and increase the productivity of Project investigators.

生物统计学和数据管理核心核心D将支持数据管理的所有阶段和 该P01项目中的分析。它将创建和管理新旧遗传，病理学和 来自四个参与研究的问卷数据。它将制定并维护准备程序 并使用安全方法在研究之间分发数据集。它将与内核B和C合作 研究设计和抽样方案的项目领​​导者为各种项目。它将提供方法论 以及针对项目研究人员的分析专业知识，包括研究设计，数据分析计划的行为， 生物信息学分析和统计结果的解释。核心将负责数据 协调使所有研究人员都使用相同的变量定义。核心将执行许多 在数据分析中，并具有最新的硬件和软件。核心将合作 与博士后研究员和调查人员紧密相关。核心的领导者和 其他核心研究人员在遗传学研究方面具有专业知识，并且在 管理和分析大型多中心研究的数据。核心的活动将保持较高 数据收集和分析标准，保持数据的完整性，在整个范围内达到一致性 研究，并提高项目研究人员的生产率。