Tools for Optimizing Medication Safety (TOP-MEDS)

优化用药安全的工具 (TOP-MEDS)

• 批准号: 8265048
• 负责人: BRUCE L. LAMBERT
• 金额: $ 84.88万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8265048
• 关键词: Tools; Optimizing; Medication; Safety; TOP

DESCRIPTION (provided by applicant): We propose a patient safety CERT focused on the theme of Tools for Optimizing Medication Safety (TOPMEDS). The long term goal is to improve patient safety by developing and refining tools for safer medication use. The short term objective is to develop, test, deploy and disseminate tools and training materials in four key areas: statistical methods for large-scale studies of comparative drug safety and effectiveness, opioid prescribing and dosing for acute pain, methods for preventing and detecting drug name confusion errors, and patient-centered, language concordant drug information. We will carry out studies with the following specific aims: 1. Develop and apply a multivariate, person-time logistic regression model for large-scale adverse drug event screening. 2. Improve the safety and effectiveness of inpatient acute pain care by developing and validating a novel, web-based simulator to train prescribers in the proper selection and dosing of opioids. 3. Refine a standard battery of tests for pre-market safety screening of drug names, and develop and test methods for preventing and detecting drug name confusion errors using electronic medical records. 4. Rigorously evaluate a low literacy strategy for promoting safe and effective prescription medication use among English and Spanish-speaking patients in an urban primary care setting. Together the projects address all five of the programmatic interest areas: comparative effectiveness, patient safety, development of tools, health care system interventions, and translation into policy or practice. UIC will host the center, with collaborators at Rush Universit Medical Center, Northwestern University, University of Chicago, the Brigham and Women's Hospital, Discerning Systems, Inc., the Institute for Safe Medication Practices, and the National Patient Safety Foundation. Our investigators are national and international leaders in statistics (Robert Gibbons), health literacy (Michael Wolf), drug name confusion (Bruce Lambert), health information technology (Gordon Schiff, Bill Galanter), pain care (Robert McNutt and Diana Wilkie) medication error prevention (Michael Cohen) and patient safety (Tim McDonald, Diane Pinakiewicz). PUBLIC HEALTH RELEVANCE: Patients are not as safe as they should be. Medication errors and inappropriate use of medicines, by health professionals and patients, cause a great deal of harm. The proposed research will make patients safer by developing and sharing tools for safer medication use, including tools for detecting drug risks, for training young doctors, for preventin medication errors and for making drug information easier to understand.

描述（由申请人提供）：我们提出了针对优化药物安全工具主题的患者安全证书（TOPMEDS）。长期目标是通过开发和完善使用更安全的用药工具来提高患者的安全。短期目标是在四个关键领域开发，测试，部署和传播工具和培训材料：用于比较药物安全性和有效性的大规模研究，阿片类药物的处方和剂量，以预防和检测药物名称束缚错误以及以患者为中心的药物，语言一致的药物信息。我们将以以下特定目的进行研究 大规模不良药物事件筛查的回归模型。 2。通过开发和验证基于Web的新型模拟器来培训处方者的适当选择和剂量的阿片类药物，提高住院急性疼痛护理的安全性和有效性。 3。精炼标准的测试，以预先进行毒品名称的预选安全筛查，并开发和测试方法，以防止和检测使用电子病历的药物名称混乱错误。 4。严格评估在城市初级保健环境中以英语和西班牙语的患者促进安全有效的处方药物使用的低扫盲策略。这些项目共同解决了所有五个程序兴趣领域：比较有效性，患者安全，工具的开发，卫生保健系统干预措施以及将其转化为政策或实践。 UIC将在Rush Universit医学中心，西北大学，芝加哥大学，杨百翰和妇女医院，灰色系统，Inc。，安全药物惯例研究所，国家患者安全基金会和国家患者安全基金会举办合作伙伴。我们的调查人员是统计学的国家和国际领导者（罗伯特·吉本），健康素养（迈克尔·沃尔夫），药物名称混乱（布鲁斯·兰伯特），健康信息技术（戈登·席夫，比尔·加兰特），疼痛护理（Robert McNutt和Diana Wilkie）药物（Robert McNutt and Diana Wilkie）药物误差（Michael Cohen）和患者安全（Michael McDonald Pinakiewiewiewiec）。 公共卫生相关性：患者不如应有的安全。卫生专业人员和患者对药物的错误和不当使用，造成了很大的伤害。拟议的研究将通过开发和共享用于使用更安全的药物使用的工具，包括用于检测药物风险的工具，培训年轻医生，预防药物错误以及使药物信息易于理解。