OBTAIN TISSUES AND ORGANS FOR HIV RESEARCH

获取用于艾滋病毒研究的组织和器官

• 批准号: 8173562
• 负责人: JOHN T LONSDALE
• 金额: $ 20.6万
• 依托单位: NATIONAL DISEASE RESEARCH INTERCHANGE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173562
• 关键词: Collection; Communities; Computer Hardware; Computer Retrieval of Information on Scientific Projects Database; Computer software; Data; Destinations; Ensure; Eye; Funding; Goals; Grant; HIV Seropositivity; Health; Hospitals; Human; Information Systems; Institution; Organ; Organ Procurements; Pathology; Preparation; Protocols documentation; Research; Research Personnel; Research Project Grants; Resources; Scientist; Shipping; Ships; Site; Source; Specific qualifier value; System; Tissue Banking; Tissue Banks; Tissue Preservation; Tissues; United States National Institutes of Health; Work; arm; data management; human tissue; improved; programs; surgical service; web site

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): The Human Tissues and Organs for Research (HTOR) program of the NDRI is dedicated solely to accessing and providing human tissues for research purposes. These tissues and organs are essential for the great majority of research projects served by HTOR and the program is clearly relevant to advancing human health. HTOR's long-term objective is to increase the quantity, diversity, and quality of human research tissues available for research. The collection, preparation, and preservation of the tissues must be performed according to researcher-specified protocols for the materials to be useful to scientists. The acquisition of these materials requires an extensive national network of acquisition sites such as hospital pathology and surgical services, eye and tissue banks, and Organ Procurement Organizations. HTOR's unique systems ensure that tissues procured for customized protocols are delivered in a timely manner to the appropriate research destinations. The quantity, quality and diversity of tissues shipped to investigators is a function of three critical variables: the number and types of sources working with HTOR, the internal systems of HTOR, and the number and types of research requests that HTOR receives from researchers. The specific aims of the proposed funding period focus on strengthening these three arms of the HTOR program (sources, information systems, and researchers). HTOR will work to increase the capabilities of existing sources and add new sources to increase tissue quantity and diversity (Specific Aim 1/Sources); upgrade HTOR's internal systems (computer hardware, software, and data management) to improve data capture and analysis, and upgrade the HTOR Web Site to increase Source and Researcher access to HTOR resources (Specific Aim 2/Systems); and work closely with the research community to fulfill existing and emerging needs for human research tissue (Specific Aim 3/Researchers). In addition, HTOR will continue a specialized program for procuring and distributing HIV positive tissues (Specific Aim 4), a goal that is also consistent with HTOR's long-term objective.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 描述（由申请人提供）： NDRI的研究（HTOR）计划的人体组织和器官仅专门用于用于研究目的的人类组织。 这些组织和器官对于HTOR提供的绝大多数研究项目至关重要，该计划显然与促进人类健康有关。 HTOR的长期目标是增加可用于研究的人类研究组织的数量，多样性和质量。 必须根据研究人员指定的方案对组织进行收集，制备和保存，以便对科学家有用。 这些材料的获取需要广泛的国家收购网站网络，例如医院病理和外科服务，眼睛和组织库以及器官采购组织。 HTOR的独特系统确保为定制协议购买的组织及时交付给适当的研究目的地。 运往研究人员的组织的数量，质量和多样性是三个关键变量的函数：与HTOR一起工作的来源的数量和类型，HTOR的内部系统以及HTOR从研究人员那里收到的研究请求的数量和类型。 拟议的资金期间的具体目的是加强HTOR计划的这三个部门（来源，信息系统和研究人员）。 HTOR将努力提高现有资源的能力，并增加新来源以增加组织数量和多样性（特定的AIM 1/源）；升级HTOR的内部系统（计算机硬件，软件和数据管理）来改善数据捕获和分析，并升级HTOR网站以增加源和研究人员访问HTOR资源（特定的AIM 2/Systems）；并与研究社区紧密合作，以满足人类研究组织的现有和新兴需求（特定的目标3/研究人员）。 此外，HTOR将继续采用和分发HIV阳性组织的专业计划（特定目标4），这个目标也与HTOR的长期目标一致。