DYNAMICS OF PROTEASOME COMPLEXES & THEIR INTERACTIONS WITH CSN COMPLEXES

蛋白酶体复合物的动力学

• 批准号: 8171000
• 负责人: Lan Huang
• 金额: $ 0.18万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171000
• 关键词: Complex; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Oxidative Stress; Research; Research Personnel; Resources; Source; Structure; United States National Institutes of Health; in vivo; interest; multicatalytic endopeptidase complex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are interested in understanding how the structures of proteasome complexes are regulated upon oxidative stress. In addition, we are trying to determine how proteasome complexes interact with the CSN complex in vivo.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 我们有兴趣了解氧化应激如何调节蛋白酶体复合物的结构。 此外，我们正在尝试确定蛋白酶体复合物如何在体内与 CSN 复合物相互作用。