RSR1 AND THE ESTABLISHMENT OF CELL POLARITY

RSR1 和细胞极性的建立

• 批准号: 8171246
• 负责人: Hay-Oak Park
• 金额: $ 0.96万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171246
• 关键词: Cell Polarity; Cells; Computer Retrieval of Information on Scientific Projects Database; Cues; Fluorescence Resonance Energy Transfer; Funding; Grant; Guanosine Triphosphate Phosphohydrolases; Institution; Location; Research; Research Personnel; Resources; Saccharomycetales; Source; United States National Institutes of Health; cell type; interest; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cell polarization occurs along a single axis that is generally determined in response to spatial cues. In budding yeast, the Rsr1 GTPase and its regulators direct the establishment of cell polarity at the proper cortical location in response to cell-type-specific cues. We are interested in exploring the interactions of Rsr1 by FRET.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 细胞极化沿单个轴发生，该轴通常根据空间提示确定。在萌芽的酵母中，RSR1 GTPase及其调节剂将在适当的皮质位置指导细胞型特异性提示，将细胞极性建立在适当的皮质位置。我们有兴趣探索FRET的RSR1相互作用。