DIFFERENTIAL SCANNING CALORIMETER UPGRADE

差示扫描量热计升级

• 批准号: 8172252
• 负责人: CURT R DUNNAM
• 金额: $ 0.32万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172252
• 关键词: Access to Information; Calorimetry; Collection; Computer Hardware; Computer Retrieval of Information on Scientific Projects Database; Computer software; Computers; Data; Data Analyses; Data Collection; Data Storage and Retrieval; Devices; Funding; Grant; Heating; Institution; Manuals; Measurement; Modeling; Research; Research Personnel; Resources; Sampling; Scanning; Signal Transduction; Source; Specialist; System; Temperature; Time; United States National Institutes of Health; Update; analog; data acquisition; digital; instrument; interest; operation; Access to Information; Calorimetry; Collection; Computer Hardware; Computer Retrieval of Information on Scientific Projects Database; Computer software; Computers; Data; Data Analyses; Data Collection; Data Storage and Retrieval; Devices; Funding; Grant; Heating; Institution; Manuals; Measurement; Modeling; Research; Research Personnel; Resources; Sampling; Scanning; Signal Transduction; Source; Specialist; System; Temperature; Time; United States National Institutes of Health; Update; analog; data acquisition; digital; instrument; interest; operation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. ACERT possesses a Perkin-Elmer model DSC-4 calorimeter which we occasionally want to employ for calorimetric measurements on samples provided by center users. This instrument is almost 30 years old and, although the calorimeter section functions well, the control interface, dedicated operating computer and data storage media are only of historical interest. Consequently, we were no longer able to store data or perform analysis with the original computing platform. To revitalize this otherwise functional instrument, we investigated the availability of a commercial aftermarket computer/control system upgrade (Instrument Specialists, Inc.) but found the available package of computer hardware with data analysis software to be both more comprehensive and more expensive than our requirements justified. Noting instead that our need was elementary, i.e., only the collection of heat flow vs. temperature data, we undertook an examination of the P-E DSC-4 apparatus and determined that extraction of appropriate signals and providing a means for their conversion to data for analysis and storage would be a reasonably straightforward task. Subsequently, we have updated the computer to a contemporary IBM-compatible unit and added an external, USB-interfaced universal data acquisition device (National Instruments, Inc.). Because we did not have access to information describing the Perkin-Elmer proprietary control signals, data collection is for now initiated by manual operation of the DSC-4 control and sample chasses at which time the computer begins collecting data. The data that is converted with the current arrangement comprises the DSC-4 heat flow rate and temperature analog signals, and a digital signal corresponding to temperature marker occurring every 10 ¿ C. We plan to develop by the end of the summer a suite of basic calorimetry analysis software routines for semiautomated analysis of the DSC-4 data.

该副本是使用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这是调查员的机构。 Acert拥有Perkin-Elmer DSC-4量热仪，我们偶尔想对中心用户提供的样品进行量热测量。该仪器已有将近30年的历史，尽管量热计部分功能良好，但控制界面，专用的操作计算机和数据存储媒体仅具有历史兴趣。因此，我们不再能够使用原始计算平台存储数据或执行分析。为了振兴这种原本功能的工具，我们研究了商业售后计算机/控制系统升级（Instrument Procecity，Inc。）的可用性，但发现带有数据分析软件的计算机硬件包装既比我们的要求更全面，更昂贵。相反，我们的需求是基本的，即仅收集热流量与温度数据，我们对P-E DSC-4设备进行了检查，并确定提取适当的信号并提供将其转换为数据进行分析和存储的手段的方法是合理的直接任务。随后，我们将计算机更新为现代IBM兼容单元，并添加了外部的USB互联网通用数据采集设备（National Instruments，Inc。）。由于我们无法访问描述Perkin-Elmer专有控制信号的信息，因此数据收集现在是通过DSC-4控制和示例底盘的手动操作来启动的，而计算机开始收集数据。用当前布置转换的数据包括DSC-4的热流速和温度模拟信号，以及与温度标志物相对应的数字信号每10€»C。我们计划在夏季结束时开发一套基本的量热法分析软件的例程，用于对DSC-4数据进行半匹配分析。