RADIAL DCE-MRI FOR ASSESSMENT OF TUMOR VASCULAR RESPONSE

用于评估肿瘤血管反应的径向 DCE-MRI

• 批准号: 8169041
• 负责人: MITCHELL D. SCHNALL
• 金额: $ 1.73万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169041
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Data; Funding; Grant; Image; Image Analysis; Institution; Kinetics; Magnetic Resonance Imaging; Morphologic artifacts; Neoplasms in Vascular Tissue; Process; Radial; Research; Research Personnel; Resolution; Resources; Sampling; Source; Speed; United States National Institutes of Health; improved; response; tumor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DCE-MRI requires high temporal sampling rate imaging for evaluation of the kinetics of contrast entry into tumors. With conventional MR imaging using rectilinear k-space acquisition, increases in acquisition speed result in decreases in image resolution and volume coverage. The use of parallel imaging can onset this partially, but can introduce additional imaging artifacts. Radial MR acquisition can be used to improve temporal data sampling rate. The use of KWIC processing retains the ability to obtain high-resolution images.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 DCE-MRI 需要高时间采样率成像来评估造影剂进入的动力学 进入肿瘤。对于使用直线 k 空间采集的传统 MR 成像， 采集速度会导致图像分辨率和体积覆盖范围降低。并行的使用 成像可以部分地引起这种情况，但会引入额外的成像伪影。径向 MR 采集 可用于提高时间数据采样率。使用 KWIC 处理保留了能力 以获得高分辨率图像。