MULTIPLE ACQUISITION FAT-SATURATED BALANCED SSFPIMAGING

多次采集脂肪饱和平衡 SSFP 成像

• 批准号: 8169880
• 负责人: MARCUS T ALLEY
• 金额: $ 1.85万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169880
• 关键词: Address; Computer Retrieval of Information on Scientific Projects Database; Equilibrium; Fatty acid glycerol esters; Frequencies; Funding; Grant; Image; Institution; Lead; Methods; Morphologic artifacts; Phase; Research; Research Personnel; Resolution; Resources; Signal Transduction; Source; Time; United States National Institutes of Health; Variant; clinical application; saturated fat

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. While balanced-SSFP (bSSFP) imaging is advantageous in its ability to produce high SNR in short imaging times, its clinical application has been limited due to several well-known shortcomings. The bright signal from fat is typically unwanted, and the short repetition times (TRs) required to avoid banding artifacts lead to limitations in the achievable resolution. This is especially true at higher field strengths where SAR considerations begin to limit the minimum possible TRs. To address these problems previous methods have combined multiple bSSFP acquisitions with different linearly-increasing excitation phases to either reduce signal variations with frequency (dark bands) or suppress fat. Here we propose the addition of fat suppression to a multiple phase-cycled, 3D bSSFP acquisition to address both issues simultaneously.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 虽然平衡 SSFP (bSSFP) 成像的优势在于能够在短时间内产生高信噪比，但由于几个众所周知的缺点，其临床应用受到限制。 来自脂肪的明亮信号通常是不需要的，并且避免条带伪影所需的短重复时间（TR）会导致可实现的分辨率受到限制。 在较高场强的情况下尤其如此，此时 SAR 考虑因素开始限制可能的最小 TR。 为了解决这些问题，以前的方法将多个 bSSFP 采集与不同的线性增加激励相位相结合，以减少信号随频率（暗带）的变化或抑制脂肪。 在这里，我们建议在多相循环、3D bSSFP 采集中添加脂肪抑制，以同时解决这两个问题。